Oxygen Reserve Index
Conditions
Keywords
Oxygen reserve index, Minimal flow anesthesia, High flow anesthesia, Hypoxia, Hyperoxia
Brief summary
Our primary objective is to determine whether oxygen reserve index ORI can be a reliable and sensitive indicator of hypoxia and hyperoxia in low-flow anesthesia settings. Our secondary objective is to investigate the ORI changes during preoxygenation stage.
Interventions
DEVICEOxygen reserve index
Measuring oxygen reserve index during preoxygenation and under general anesthesia
Sponsors
Sakarya University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* ASA I-III patients * 18-75 years old * underwent general anesthesia * elective ear, nose and throat surgery, lasting longer than 60 minutes
Exclusion criteria
* who did not consent to participate, * those with finger deformities * unregulated diabetes mellitus, severe heart, kidney, or liver failure, sensitivities to local anesthetics or opioids, those who were morbidly obese (BMI >40 kg/m²), and breastfeeding women.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Oxygen Reserve Index Value | For each patient, from preoxygenation stage to the end of the general anesthesia | The Oxygen Reserve Index (ORI) is a real-time monitoring measure that captures the oxygen reserve status in the moderate hyperoxic range (PaO2 approximately 100 to 200 mmHg). ORI provides early warning of potential oxygenation disturbances before any changes occur in SpO2 and indicates the response to oxygen therapy. ORI ranges from 1 (high reserve) to 0 (no reserve) and measures changes in mixed venous oxygen saturation (SvO2) optically after arterial oxygen saturation reaches 100%. |
Countries
Turkey (Türkiye)
Outcome results
None listed