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Blood Lactate Level With Paraaortic Lymph Node Dissection

The Effect of Blood Lactate Levels on Postoperative Gastrointestinal Morbidity After Paraaortic Retroperitoneal Lymph Node Dissection

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06648330
Enrollment
75
Registered
2024-10-18
Start date
2023-09-01
Completion date
2024-09-20
Last updated
2024-10-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynaecologic Cancer, Morbidity

Keywords

major open gynaecological cancer surgery, paraaortic lymph node dissection, gastrointestinal complications

Brief summary

This study was designed as a prospective observational study.

Detailed description

In this study, the investigator planned to evaluate the effect of blood lactate levels on postoperative gastrointestinal morbidity after paraaortic retroperitoneal lymph node dissection. In gynaecological surgeries, following the removal of the intestines from the surgical field, the retroperitoneal space is entered and the main vessels such as the vena cava inferior and aorta are accessed through the left or right approach depending on the experience and habit of the per-operative surgeon, and total systemic lymph node dissection or bulky lymph node excision is performed depending on the case. During the removal of the intestines from the surgical field, hypoperfusion may develop due to decreased blood flow to the intestines. for this purpose, the investigator planned to investigate the relationship between the change in blood gas lactate values and postoperative gastrointestinal complications in this process.

Interventions

PROCEDUREParaaortic retroperitoneal lymph node dissection

The relationship between lactate level and mesenteric ischaemia in gynaecological cancer surgeries with paraaortic retroperitoneal lymph node dissection will be evaluated.

Sponsors

Duygu Akyol
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* 18 years * Patients undergoing paraaortic retroperitoneal lymph node dissection

Exclusion criteria

* Patients with chronic lung disease * Patients with inflammatory bowel disease

Design outcomes

Primary

MeasureTime frameDescription
intraoperative lactate levelsintraoperativelyChange from baseline in lactate levels in paraaortic lymph node dissection

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026