Relationship Between Postoperative Tempeartive and Acute Kidney Injury

Relationship Between First 12-h Body Temperature and Acute Kidney Injury After Valvular Heart Surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06647771

Enrollment

3274

Registered

2024-10-18

Start date

2024-08-12

Completion date

2026-08-11

Last updated

2024-10-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients Undergoing Valvular Heart Surgery

Brief summary

The investigators aimed to identify body temperature trajectory classes based on core temperature changes during the first 12 hours post-surgery and to explore their relationship with postoperative acute kidney injury in patients undergoing valvular heart surgery.

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients who underwent valvular heart surgery between January 2016 and July 2023 at Severance Cardiovascular Hospital of Yonsei University Health System

Exclusion criteria

* Patients who underwent the same surgery within 30 days, * Patients with less than two temperature measurements within 12 hours after surgery, - Patients with missing creatinine test values before and within seven days after surgery, * Patients who died during surgery

Design outcomes

Primary

Measure	Time frame	Description
acute kidney injury ≥ stage 2 according to the KDIGO criteria	seven days after valvular heart surgery	According to the KDIGO criteria, postoperative acute kidney injury of stage 2 or higher was defined as a 100% increase in creatinine within the first seven days after surgery. The association between stage 2-3 acute kidney injury and postoperative body temperature trajectory classes was investigated.

Secondary

Measure	Time frame	Description
non-recovery from acute kidney injury within 48	72 hours after the onset of acute kidney injury	The association between postoperative body temperature trajectory classes and non-recovery from acute kidney injury was investigated at two time points: within 48 hours
non-recovery from acute kidney injury within 72 hours	72 hours after the onset of acute kidney injury	The association between postoperative body temperature trajectory classes and non-recovery from acute kidney injury was investigated at two time points: within 72 hours.

Countries

South Korea

Outcome results