Association Between Post-operative Anemia and Mortality After Valvular Heart Surgery

Association Between Remote Post-operative Anemia and Mortality in Patients Undergoing Valvular Heart Surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06647758

Enrollment

3000

Registered

2024-10-18

Start date

2024-07-22

Completion date

2025-07-21

Last updated

2024-10-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients Undergoing Valvular Heart Surgery

Brief summary

The investigators aimed to evaluate whether postoperative anemia can predict 1-year mortality after valvular heart surgery independent of preoperative anemia. Patients who underwent valvular heart surgery were divided into four groups according to whether or not they had preoperative and postoperative anemia. Postoperative one-year mortality, as well as overall mortality and a composite of death and heart failure requiring hospitalization, was investigated according to the groups, adjusted by confounders.

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients who underwent valvular heart surgery between January 2016 and July 2023 at Severance Cardiovascular Hospital of Yonsei University Health System.

Exclusion criteria

* patients who underwent only pulmonary valve surgery * those with missing hemoglobin values at 2months after the surgery, due to loss of follow up or death.

Design outcomes

Primary

Measure	Time frame	Description
postoperative 1-year mortality	One year after valvular heart surgery	The investigators assessed all-cause mortality during one year after valvular heart surgery and evaluated its association with preoperative and postoperative anemic status.

Secondary

Measure	Time frame	Description
overall mortality	postopeartive one-year	The investigators assessed overall mortality during the follow-up period and a composite of death and congestive heart failure (CHF) requiring rehospitalization during the postoperative one-year and evaluated their associations with preoperative and postoperative anemic status.
composite of death and congestive heart failure (CHF) requiring rehospitalization	postopeartive one-year	The investigators assessed overall mortality during the follow-up period and a composite of death and congestive heart failure (CHF) requiring rehospitalization during the postoperative one-year and evaluated their associations with preoperative and postoperative anemic status.

Countries

South Korea

Outcome results