Skin Grafts
Conditions
Brief summary
To determine if application of Myriad Matrix to split thickness skin graft donor sites improves post-operative pain and appearance of the wound.
Detailed description
In the head and neck practice at UAB, split thickness skin grafts are a commonly used procedure for simple reconstruction. The standard dressing for donor sites is a strip of vaseline gauze which remains on the site the wound dries, and the gauze eventually falls off. Post operative pain and poor wound healing is a well established complication of the donor site, and various methods have been studied in an attempt to reduce these complications for patients in the post operative period. (1, 2, 3) Myriad matrix is an engineered extracellular matrix (Ovine Forestomach Matrix) used for soft issue repair in complex wounds. This has been sporadically used by some of the faculty members at UAB for split thickness skin graft donor site dressings with anectodal improvement in pain and healing, though this has not yet been studied to our knowledge.
Interventions
PROCEDUREMatrix Dressing
extracellular matrix dressing soaked in 4% topical lidocaine to the skin graft donor site
Sponsors
University of Alabama at Birmingham
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients 18 and over who are undergoing a split thickness skin graft at UAB.
Exclusion criteria
* Patients who are not planned to undergo a split thickness skin graft or who are unable or do not plan to attend follow up appointments will not be included.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain Improvement | 48 hours, 2 weeks, 4-6 weeks post operative visit | patients will rate pain level at donor site |
| Wound Healing | 2 weeks and 4-6 weeks post operative visit | Patients will rate appearance of would using the scar-Q questionnaire |
Outcome results
None listed