Interest of Impedancemetry in Monitoring Hydration and Hyponatremia During Subarachnoid Hemorrhages

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06646484

Acronym

BIASHA

Enrollment

100

Registered

2024-10-17

Start date

2024-12-30

Completion date

2026-01-21

Last updated

2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subarachnoid Hemorrhage (SAH)

Keywords

subarachnoid hemorrhage, impedancemetry, hydration

Brief summary

Subarachnoid hemorrhage (SAH) is a rare and serious form of stroke, mainly linked to the rupture of an intracranial aneurysm responsible for bleeding into the meningeal spaces. The main late serious complication is delayed cerebral ischemia (DCI), resulting in the appearance of new neurological deficits. Prevention of ICR involves in particular maintaining euvolemia, and early treatment of hyponatremia, itself dependent on the level of volume. Evaluation of water status and sodium balance is therefore essential. This assessment is complicated and relies on indirect parameters, both clinical and biological. Impedancemetry, making it possible to measure water volumes and sodium load, could be an aid in the management of blood volume and sodium intake.

Interventions

DIAGNOSTIC_TESTImpedancemetry evaluation

Each patient eligible for the study will, additionally to the standard care, have repeated measure of impedancemetry along their hospital stay ; Theses measure will be compared to the usual measure of hydration and natremia and agreement between clinical status of interest will be discussed.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adult man, woman * Hospitalized following Subarachnoid Hemorrhage within 72 hours of bleeding * Admitted to the neurological intensive care unit for less than 48 hours * Being able to understand the ins and outs of the study * Having expressed his non-opposition

Exclusion criteria

* Patients under legal protection * Pregnancy

Design outcomes

Primary

Measure	Time frame	Description
Hydration measurements	Every 48 hours during the mean 21 days of stay in the neurological ICU.	The level of hydration is quantified by the indicator Hydration of non-fat mass in% using the impedancemetry. Threshold values for hydration indices are specific to the measurement performed on the patient and depend on their age, gender and body composition data.

Countries

France

Contacts

Primary ContactThomas RITZENTHALER, MD

Thomas.ritzenthaler@chu-lyon.fr04.72.11.66.02

Backup ContactJulien BERTHILLER

Julien.berthiller@chu-lyon.fr04 27 85 63 01

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026