Neonatal Early-onset Sepsis
Conditions
Keywords
Neonatal early onset sepsis, Kaiser Permanente calculator
Brief summary
Early neonatal sepsis requires rapid and efficient intervention to prevent morbidity and mortality. Management of such a case includes invasive blood examinations, elongation of maternal and neonatal length of stay, and empiric antibiotic therapy. These actions has major side effects. On 2017, Kaiser-Permanente started using a calculator that weighs the chances for early onset neonatal sepsis, and states the best investigation and follow-up regimn for the specific newborn infant. Eversince, policy of managing neonatal suspected early onset sepsis has chaged globally, including in Israel. Current knowledge regarding the local outcome since the use of the calculatir is scarce. The goal of the study is to evaluate the change in management of suspected neonatal early onset sepsis, including its economic value, between periods before and after assimilation of the calculator in Hillel Yaffe nedica l center.
Detailed description
Early neonatal sepsis requires rapid and efficient intervention to prevent morbidity and mortality. Management of such a case includes invasive blood examinations, elongation of maternal and neonatal length of stay, and empiric antibiotic therapy. These actions has major side effects. On 2017, Kaiser-Permanente started using a calculator that weighs the chances for early onset neonatal sepsis, and states the best investigation and follow-up regimn for the specific newborn infant. Eversince, policy of managing neonatal suspected early onset sepsis has chaged globally, including in Israel. Current knowledge regarding the local outcome since the use of the calculatir is scarce. The goal of the study is to evaluate the change in management of suspected neonatal early onset sepsis, including its economic value, between periods before and after assimilation of the calculator in Hillel Yaffe nedical center.
Interventions
OTHERNo intervention
No intervention
Sponsors
Hillel Yaffe Medical Center
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 7 Days
Healthy volunteers
No
Inclusion criteria
* Newborn unfants born in Hillel Yaffe medical center * 35 weeks of gestation or more * Blood culture was taken
Exclusion criteria
* Sepsis workup for other reason * 34 weeks of gestation or less
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of negative blood cultures out of all blood cultures | during first week of life | Total count of negative blood cultures out of all blood cultures in all patients in group |
| Number of positive blood cultures | during first week of life | Total count of positive blood cultures in all patients in group |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cost of treatment | during first week of life | Total cost of Blood cultures + Blood counts + Antibiotic therpy in all patients in group |
Countries
Israel
Contacts
CONTACTErez Nadir, MD
PRINCIPAL_INVESTIGATORErez Nadir, MD
Hillel Yaffe Medical Center
Outcome results
None listed