Predictive Model
Conditions
Keywords
predicted model, major non-cardiac surgery, elderly patients, anxiety
Brief summary
A multicentre, prospective observational study to develop and validate a predictive model for postoperative anxiety symptoms in elderly Chinese patients undergoing non-cardiac major surgery.
Detailed description
In 2015, the WHO introduced the concept of healthy ageing for global ageing, with a focus on the mental health of older people at its core. More than 20 million elderly patients undergo surgery each year in China, accounting for a quarter of the population who undergo surgery. Previous studies have found high risk of anxiety in older perioperative patients, especially for non-cardiac major surgery patients. Therefore, it is necessary to construct a predictive model of anxiety in elderly patients undergoing non-cardiac major surgery.
Interventions
None listed
Sponsors
Beijing Tiantan Hospital
Peking University First Hospital
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Xiangya Hospital of Central South University
Beijing Anzhen Hospital
Central South University
Peking University People's Hospital
Zhejiang University
Fudan University
Sun Yat-sen University
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
China-Japan Friendship Hospital
The Affiliated Hospital Of Guizhou Medical University
First Affiliated Hospital of Xinjiang Medical University
First Affiliated Hospital of Guangxi Medical University
Taihe Hospital
Zhejiang Provincial People's Hospital
Shanghai Zhongshan Hospital
Chinese PLA General Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
65 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
1. Elderly patients (age ≥ 65 years). 2. Undergoing elective surgery with a planned overnight hospital stay following surgery. 3. Major non-cardiac surgery, non-neurosurgical surgery.
Exclusion criteria
1. History of previous severe mental illness or long-term use of psychotropic medications. 2. Immediately admitted to ICU after surgery. 3. Death within 7 days after surgery. 4. Grade of surgery ≤ 2. 5. Failure to complete the postoperative anxiety assessment.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Anxiety | within 7 days after surgery | The GAD-7 is a seven-item questionnaire for screening on the presence of generalized anxiety disorder and assessing its severity. Items were scored on a four-point scale with total scores ranging from zero to twenty-one. Scores were defined as: ≥5 mild, ≥10 moderate, and ≥15 severe anxiety. The recommended screening cutoff was ≥10, corresponding with at least a moderate level of anxiety. Higher scores mean more anxiety. |
Countries
China
Outcome results
None listed