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Diagnostic and Management of Hand Infection.

Diagnostic and Management of Hand Infection: a Retrospective Cohort in a Tertiary Care Center.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06630988
Acronym
HandInf
Enrollment
1400
Registered
2024-10-08
Start date
2024-09-01
Completion date
2025-06-30
Last updated
2024-10-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hand Infections, Including Whitlows, Septic Arthritis, Tendinous Infections

Keywords

Hand infection, Whitlows, Tendinous infections, Septic arthritis

Brief summary

Primary or secondary (post-traumatic infections, notably related to bites, wounds, etc.) infections of the hand are very common situations, even if the epidemiology is poorly understood. For example, hand bite injuries represent 1.2 million referrals to the healthcare system per year in the United States. Their nosological framework extends from simple infections of the skin and soft tissues such as whitlows, to potentially severe deep damage such as arthritis and osteitis, or phlegmons of the tendon sheaths. The diagnostic approach is not consensual, and the contribution of additional biological parameters (inflammatory syndrome) and morphological investigations (x-rays, ultrasound, CT-scan or MRI) is not codified. Microbiology seems dominated by Staphylococcus aureus, but few studies have precisely described the microbial etiology. Consequently, probabilistic antibiotic therapy and the need to take bacteriological samples for secondary adaptation are not standardized. Likewise, surgical strategies (abstention, systematic washing or depending on evolution) remain operator dependent. We consequently aim to described diagnostic, management and related outcomes or hand infections in a specialized tertiary care center.

Interventions

OTHERFailure rates

Describe the management failure rate for hand infections, including panariasis, phlegmons and arthritis.

Sponsors

Hospices Civils de Lyon
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* all patient ≥ 18 * yo followed-up for a hand infection in our tertiary care center * from 01/01/2014 to 31/12/2023, including * whitlows * tendinous infections * septic arthritis

Exclusion criteria

* osteomyelitis

Design outcomes

Primary

MeasureTime frameDescription
Percentage of treatment failure during the management of hand infections.between 01/01/2014 and 31/12/2023.Treatment failure will be defined as infection persistence or relapse, need of unplanned surgery for septic reason or infection-related death.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026