Optimization of Management in Patients With Cardiovascular Disease After Lower Limb Joint Replacement

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06627933

Enrollment

1733

Registered

2024-10-04

Start date

2023-01-15

Completion date

2027-09-10

Last updated

2026-05-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anticoagulant-induced Bleeding, Thromboembolism

Keywords

joint replacement, prognosis, anticoagulation regimen, thromboembolism, venous thromboembolism

Brief summary

The goal of the study is to evaluate the frequency of cardiovascular and thromboembolic complications in patients with cardiovascular disease after lower limb joint replacement, the influence of known risk factors and strategies for perioperative prevention of thromboembolic complications on the frequency of cardiovascular complications and to develop approaches to optimize antithrombotic prevention tactics.

Interventions

OTHERNo intervention

No intervention

Study design

Observational model

ECOLOGIC_OR_COMMUNITY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 95 Years

Healthy volunteers

Inclusion criteria

* Informed consent * Age older than 18 y.o. * Cardiovascular disease * Indications for planned lower limb joint replacement surgery

Exclusion criteria

* Pregnancy * Psychiatric disorders * Decompensated heart failure or acute heart failure * Known diagnosis of cancer

Design outcomes

Primary

Measure	Time frame	Description
Bleeding	1 month	All the cases of major and minor bleeding within 1 month
Thromboembolism	1 month	All the cases of venous thromboembolism within 1 month

Countries

Russia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 15, 2026