Skip to content

SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Immigrant Families

SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Immigrant Families

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06627764
Acronym
SER Familia
Enrollment
400
Registered
2024-10-04
Start date
2025-06-30
Completion date
2029-01-31
Last updated
2026-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety, Depression, HIV Infections, Intimate Partner Violence (IPV), Substance Abuse

Keywords

Family, Stress, Resilience

Brief summary

This study aims to prevent syndemic health conditions by decreasing acculturative stress and promoting resilience via SER Familia (Salud, Estrés y Resilencia en Familias/ Health, Stress, and Resilience in Families), a family-based intervention. SER Familia is a six-session intervention co-developed and delivered by community health workers (CHWs) that uses strategies to reduce acculturative stress, promote resilience, improve parent-child and family level health, while simultaneously helping families maintain strong social networks and better navigate community resources to address social determinants of health (SDOH). More specifically, investigators aim to: 1) Examine the efficacy of SER Familia to prevent or reduce the syndemic comprised of substance abuse, IPV, HIV risk, depression, and anxiety among Parents and Youth; and 2) Identify how individual, family, and community mechanisms of change related to acculturative stress and resilience mediates the effect of SER Familia.

Interventions

BEHAVIORALSER Familia

SER Familia is a six-session intervention co-developed and delivered by community health workers (CHWs) that uses strategies to reduce acculturative stress, promote resilience, improve parent-child and family level health, while simultaneously helping families maintain strong social networks and better navigate community resources to address social determinants of health (SDOH).

Sponsors

Duke University
Lead SponsorOTHER
National Institute on Minority Health and Health Disparities (NIMHD)
CollaboratorNIH

Study design

Allocation
RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
12 Years to 100 Years
Healthy volunteers
Yes

Inclusion criteria

* Eligible participants must identify as Hispanic/Latino/a/x/e, * be a first generation immigrant parent or parental figure (Parent) * have a child (Youth) aged 12-17 * speak English and/or Spanish

Exclusion criteria

* Families planning to move within two years will be excluded

Design outcomes

Primary

MeasureTime frameDescription
Change in Parent Acculturative stress as measured by the Hispanic Stress Inventory (HSI-2) Immigrant VersionFrom Enrollment to end of treatment at 6 weeksThe immigrant version of the HSI-2 includes 10 stress subscales. For each item, participants indicated whether they had experienced the stressor (Yes / No). If participants reported experiencing a stressor, then they rated how stressful the event was on a 5-point Likert scale (1= Not at all worried / tense; 2 = A little worried / tense; 3 = Moderately worried / tense; 4 = Very worried/ tense; 5 = Extremely worried/ tense). The total score ranges from 94 to 470, where a higher score indicates greater stress.
Change in Youth Acculturative stress as measured by the Hispanic Stress Inventory - Adolescent (HSI-A)From Enrollment to end of treatment at 6 weeksThe HSI-A includes 8 stress subscales. For each item, participants indicated whether they had experienced the stressor (Yes / No). If participants reported experiencing a stressor, then they rated how stressful the event was on a 5-point Likert scale (1= Not at all worried / tense; 2 = A little worried / tense; 3 = Moderately worried / tense; 4 = Very worried/ tense; 5 = Extremely worried/ tense). The total score ranges from 72 to 360, where a higher score indicates greater stress.
Change in individual resilience as measured by the 25-item Resiliency ScaleFrom Enrollment to end of treatment at 6 weeksThe Resiliency Scale uses a 7-point Likert scale to assess how much a respondent agrees or disagrees with statements. The possible total score ranges from 25 to 175, with higher scores indicating greater resilience. Scores above 145 indicate high resilience, 121 to 145 indicate moderate resilience, and below 120 indicate low resilience.
Change in PROMIS (Patient-Reported Outcomes Measurement Information System) Global HealthFrom Enrollment to end of treatment at 6 weeksThe PROMIS Global Health score ranges from 10 to 50, where a higher score indicates better overall health.

Countries

United States

Contacts

CONTACTRosa Gonzalez-Guarda, PhD
rosa.gonzalez-guarda@duke.edu9196132634
CONTACTNorma Garcia-Ortiz, BS
norma.garcia.ortiz@duke.edu9196849331

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 10, 2026