Aortic Aneurysm, Aortic Dissection
Conditions
Brief summary
The goal of this observational study is to learn about the effect of different hypotensive drugs on the prognosis of postoperative aortic patients. The main question it aims to answer is: Does different hypotensive drugs influence the prognosis of postoperative aortic patients? As participants already taking hypotensive drugs as part of their regular medical care, the investigators collect the participants' pre-operation medical record and post-operative follow-up record to evaluate the aorta condition.
Detailed description
This study is a cohort study that aims to explore the effects of different antihypertensive regimens on aortic remodelling in patients after aortic surgery by collecting the hospitalization and outpatient follow-up data. The study plans to gather perioperative and postoperative follow-up data from over 600 patients who underwent aortic surgery at the Eighth Affiliated Hospital and Beijing Anzhen Cardiothoracic Surgery Center. Patients were assigned based on the postoperative antihypertensive medication regimens. Datas was collected to compare the cardiovascular-related prognoses. This study primarily includes patients who take oral antihypertensive medications after aortic surgery. The main observations will focus on postoperative complications related to the aorta (such as death, reoperation, dilation, etc.) and aortic diameters after the administration of different antihypertensive medications. Multivariate regression analysis will be employed to investigate the impact of different antihypertensive regimens on patients after aortic surgery.
Interventions
Postoperative antihypertensive medication includes CCB
Postoperative antihypertensive medication does not include CCB
Sponsors
Study design
Eligibility
Inclusion criteria
* aortic diseases' patients underwent aortic surgery who require antihypertensive medication.
Exclusion criteria
* Patients with active vasculitis; * Patients allergic to contrast agent * Patients with aorta variation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Aortic diameter | Through the study completion, on an average of 3 years | The maximum diameter of the aorta measured by computed tomography angiography |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of Participants with adverse aortic event | Through the study completion, on an average of 3 years | Postoperative adverse aortic event during follow-up, including aortic related death or reoperation |