Papillary Thyroid Carcinoma
Conditions
Keywords
iodine status, papillary thyroid carcinoma
Brief summary
The effect of iodine on papillary thyroid cancer has been controversial for many years. The investigators designed a cross-sectional study and aimed to explore the relationship between the serum and urine iodine levels and the clinical and molecular characteristics of papillary thyroid cancer.
Interventions
DIETARY_SUPPLEMENTIodine excess
Iodine excess areas: water iodine ≥100μg/L; or urinary iodine concentration(median urinary iodine levels in children aged 8-10 years old) ≥300μg/L
DIETARY_SUPPLEMENTIodine suitable
Iodine suitable areas: water iodine ≥40μg/L and ≤100μg/L; or urinary iodine concentration(median urinary iodine levels in children aged 8-10 years old) 100-199μg/L.
Sponsors
Shandong Provincial Hospital
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Age range: 18\ 65 years old, gender not limited; * Living in the residential area for at least 5 years; * Patients diagnosed clinically with thyroid cancer and scheduled for thyroid surgery, with pathological diagnosis of papillary thyroid cancer; * Complete clinical data: including general information, relevant laboratory tests, pathological reports, surgical reports, ultrasound reports, etc.
Exclusion criteria
* Pathological diagnosis of other types of thyroid cancer; * Diagnosed with other types of cancer; * There are serious comorbidities of the heart, liver, and kidneys;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum and urine iodine levels | 1 year from enrollment |
| TNM staging of papillary thyroid cancer | 3 month from enrollment |
Contacts
Primary ContactQingling Guo
Outcome results
None listed