Heart Failure
Conditions
Brief summary
The aim of this study was to investigate the effect of intra-session exercise modes sequence on ventricular function in patients with chronic heart failure.
Detailed description
Sixty male patients with chronic heart failure will be recruited in this study from National Heart Institute Giza, Egypt. Their ages will be ranged from 55 to 65 years old and they will be randomly divided into three groups as following: 1. Study group (A) includes 20 patients who will receive intra-session exercise modes sequence of aerobic cardiovascular training (CVT) then resistance training (RT) exercises in addition to routine treatment programme. 2. Study group (B) includes 20 patients who will receive intra-session exercise modes sequence of resistance training (RT) then aerobic cardiovascular training (CVT) exercises in addition to routine treatment programme. 3. Control group (C) includes 20 patients who will receive routine treatment programme only. The exercise training programme for both study groups A and B will be applied once per day, three times per week for 12 consecutive weeks. Inclusion criteria: All participated patients will be: * Male patients with chronic heart failure and ages from 55 to 65 years old. * Class II and class III heart failure according to NYHA classification. * HFrEF category with LVEF \<40% as documented by echocardiogram within \<6 months. * Receiving the same medical treatment programme for at least 3 months. * Having a close level of functional capacity assessed by 6 minute walking test. Exclusion criteria: Patients who meet one of the following criteria will be excluded: * Uncontrolled atrial fibrillation. * Diabetes mellitus. * Myocardial infarction or recurrent angina within \<3 months. * Patients with chronic chest diseases. * Severe stenotic valvular disease. * Clinically significant peripheral vascular disease. * Exercise-induced angina, ST segment changes or exercise induce AV block. * Patients with chronic renal failure. * Any cognitive impairment that interferes with prescribed exercise procedures. * Musculoskeletal or neurological limitation to physical exercise. RESEARCH ETHICS The protocol of this study will be approved by the ethics committee of scientific research at the Faculty of Physical Therapy, Cairo University. The study procedure will be explained in details for every patient before the initial assessment. All patients will be informed about the purpose, nature, and potential risks of the study, and a written informed consent will be obtained before participation in the study. The participants' right confidentiality will be observed strictly.
Interventions
OTHERresistance and aerobic training exercises
resistance and aerobic training exercises
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
MALE
Age
55 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Male patients with chronic heart failure and ages from 55 to 65 years old. * Class II and class III heart failure according to NYHA classification. * HFrEF category with LVEF \<40% as documented by echocardiogram within \<6 months. * Receiving the same medical treatment programme for at least 3 months. * Having a close level of functional capacity assessed by 6 minute walking test
Exclusion criteria
* • Uncontrolled atrial fibrillation. * Diabetes mellitus. * Myocardial infarction or recurrent angina within \<3 months. * Patients with chronic chest diseases. * Severe stenotic valvular disease. * Clinically significant peripheral vascular disease. * Exercise-induced angina, ST segment changes or exercise induce AV block. * Patients with chronic renal failure. * Any cognitive impairment that interferes with prescribed exercise procedures. * Musculoskeletal or neurological limitation to physical exercise.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Left ventricular ejection fraction | 12 weeks | left ventricular ejection fraction is measured by using echocardiography it is measured in percentage % |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The Minnesota living with heart failure questionnaire (MLWHFQ) | 12 weeks | calculate minnasota living with heart failure questionnaire score 21 item MLHFQ uses a 6-point scale where 0 = no, 1= very little and 5= very much |
| Cardiorespiratory fitness 6 minute walk test | 12 weeks | after the test we calculate the distance patient walked in meters and we use this distance to evaluate the cardiopulmonary fitness |
| Vo2 Max | 12 week | by using distance from the 6MWT in meters we can calculate the vo2 max using specific equation |
| Blood pressure | 12 weeks | blood pressure systolic by using the sphygmomanometer palpatory method - diastolic by using the auscultatory method by sphygmomanometer and stethoscope |
| Rate of pressure product | 12 week | rate pressure product will be calculated by this equation : patient heart rate \* systolic blood pressure / 1000 |
Countries
Egypt
Outcome results
None listed