Ultrasound-Guided Serratus and Transversus Thoracic Muscle Plane Block Vs. Erector Spinae Plane Block for Acute Poststernotomy Pain

Comparison of Ultrasound-Guided Serratus Anterior and Transversus Thoracic Muscle Plane Block Combination Versus Erector Spinae Plane Block for Acute Poststernotomy Pain Management After Cardiac Surgery

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06625580

Enrollment

Registered

2024-10-03

Start date

2023-09-01

Completion date

2024-07-01

Last updated

2024-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain, Acute, Pain, Chest

Brief summary

Poststernotomy pain represents a complication that can arise following cardiac surgery. Inadequately managed pain has been linked to various adverse outcomes, including myocardial ischemia, cardiac arrhythmias, heightened coagulation tendencies, pulmonary complications, and elevated incidences of delirium and wound infections. The Erector Spinae Plane (ESP) block, Serratus Anterior Plane (SAP) block, and Transverse Thoracic Muscle Plane (TTMP) block are demonstrated as effective regional anesthesia techniques for sternotomy pain. While these blocks differ in ease of application and efficacy, the optimal analgesic approach for cardiac surgery remains unclear. The aim of this study is to compare the analgesic efficacy of ultrasound-guided SAP and TTMP blocks combination versus ESP block administered alone in patients undergoing open heart surgery.

Interventions

PROCEDUREtransverse thoracic muscle plane and serratus anterior plane block

ultrasound guided transverse thoracic muscle plane block and serratus anterior plane block will be performed with 0.25% bupivacaine

PROCEDUREerector spinae plane block

ultrasound guided erector spinae plane block will be performed with 0.25% bupivacaine

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

* Cardiac Surgery with median sternotomy (valvular and coronary surgeries)

Exclusion criteria

* Minimal invasive cardiac surgeries * Revision surgeries (during postoperative 48 hours) * Redo cardiac surgeries * Any contraindications for regional anesthesia technique (any allergies for local anesthetics) * Preoperative chronic opioid usage

Design outcomes

Primary

Measure	Time frame	Description
Postoperative opioid consumption	Postoperative 48 hours	postoperative opioid consumption will be recorded for 48 hours

Secondary

Measure	Time frame	Description
Postoperative Visual Analog Scale	Postoperative 48 hours	Postoperative Visual Analog Scale assessment will be performed

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026