Delirium on Emergence
Conditions
Brief summary
The purpose of this study is to measure the incidences of pediatric emergence delirium between the group receiving Isoflurane and the group receiving Sevoflurane plus intravenous push dexmedetomidine.
Interventions
DRUGSevoflurane
Subjects will receive standard of care anesthesia Sevoflurane, with intravenous push Dexmedetomidine
DRUGIsoflurane
Subjects will receive standard of care anesthesia Isoflurane
Sponsors
Mayo Clinic
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
2 Years to 7 Years
Healthy volunteers
No
Inclusion criteria
* Pediatric patients aged 2-7 years. * Surgeries include ENT cases (i.e., tonsillectomy/adenoidectomy), ophthalmology cases (i.e., strabismus), and urology cases. * Can be outpatient or General Care inpatient procedures. * All cases must include an IV and an endotracheal tube (ETT).
Exclusion criteria
* Severe developmental/cognitive delay (unable to make eye contact, nonverbal, or inability to interact with providers for PAED scale assessment requirements) * TIVA cases. * No PIV in place during the case, planned PICU admission postoperatively. * Previous history of severe emergence delirium documented by a provider (via interventions or explicitly stated).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of subjects with emergence delirium | Within 1 hour after dropped off by anesthesiology team | Total number of subjects with a Pediatric Anesthesia Emergence Delirium (PAED) score of \> 10. The PAED scale consists of 5 criteria that are scored using a 5-point scale. The scores of each criterion are added to make a total score. The maximum achievable total score is 20. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Post Anesthesia Care Unit (PACU) length of stay | Post-procedural (0-4 hours after anesthesiology drop off) | Number of hours spent in PACU during recovery |
Countries
United States
Contacts
Primary ContactLindsay Warner, MD
Backup ContactMolly Herr, MD
Outcome results
None listed