Bruxism
Conditions
Keywords
melatonin, saliva, cortizol
Brief summary
The effects of the hormones melatonin and cortisol, which play a highly effective role in regulating the sleep-wake cycle, on teeth grinding will be scientifically evaluated. Based on the research results, more effective methods for treating patients suffering from bruxism may be identified.
Interventions
DIAGNOSTIC_TESTThe investigation of melatonin and cortisol levels in the saliva
In the related study, patient data from individuals who visited the Oral and Maxillofacial Radiology clinic at Van Yüzüncü Yıl University Faculty of Dentistry with complaints of bruxism will be used. The diagnosis of bruxism will be made based on clinical data. Diagnoses will be made by Dr. Sema KAYA using clinical findings such as patient history used for the current diagnosis of bruxism, tooth wear, tooth mobility, pain in the temporomandibular joint (TMJ), headaches, pain in the chewing muscles, hypertrophy, and a feeling of fatigue. Before taking the saliva samples, patients will be asked to rinse their mouths with sterile water, and then they will be asked to spit into sterile plastic containers. After approximately 3 mL of saliva is collected, it will be transferred to appropriate Eppendorf tubes and stored at -80°C. Melatonin and cortisol levels will later be analyzed using the enzyme-linked immunosorbent assay (ELISA) method.
Sponsors
Yuzuncu Yil University
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
\- Individuals without any known hormonal diseases, not using antidepressants or medications that could alter saliva content, without degenerative diseases affecting the salivary glands, without cysts or tumors affecting the temporomandibular region, and not undergoing insomnia treatment will be included in the study
Exclusion criteria
* Individuals with systemic diseases that affect or may potentially affect saliva content, or those using medications that cause these effects, will not be included in the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| levels of melatonin | Baseline assessment at the start of the study, follow-up assessments at 3 months and 6 months, with final data collection at 12 months. | individuals with bruxism |
| levels of cortisol | Baseline assessment at the start of the study, follow-up assessments at 3 months and 6 months, with final data collection at 12 months. | individuals with bruxism |
Contacts
Primary ContactSema Kaya
Outcome results
None listed