Nephrotic Syndrome
Conditions
Brief summary
nephrotic syndrome (NS) is one of the most common pediatric kidney diseases There is an increased incidence of heart disease in patients with primary nephrotic syndrome (PNS) compared to the normal population Conventional Echocardiography is usually utilized to diagnose myocardial dysfunction. Tissue Doppler imaging is a non-invasive cardiac imaging technique which measures the velocity of the longitudinal motion of the mitral annulus, tricuspid annulus and the basal part of interventricular septum
Interventions
DEVICETissue Doppler imaging and Conventional Echocardiography
non-invasive cardiac imaging technique which measures the velocity of the longitudinal motion of the mitral annulus, tricuspid annulus and the basal part of interventricular septum
Sponsors
Sohag University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
2 Years to 14 Years
Healthy volunteers
Yes
Inclusion criteria
* Children with primary nephrotic syndrome. * Age: 2 - 14 years. * Both males and females
Exclusion criteria
* Patients of primary cardiac diseases (e.g., congenital or rheumatic heart disease, cardio- myopathy). Patients who refuse to give written informed consent to study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| cardiac performance evaluation in children with steroid dependent vs steroid resistant nephrotic syndrome | 12 months | compairing of myocardial performance index (MPI)(Tei index) in nephrotic dependant and resistant nephrotic syndrom by calculating ejection time (ET) of right and left ventricle and mitral closure time (MCT) using tissue doppler |
Countries
Egypt
Contacts
Primary Contactalaa y Mohamed, Resident
Outcome results
None listed