Exanguination, NCTH, Polytrauma
Conditions
Keywords
NCTH, aortic occlusion, exanguniation
Brief summary
This study seeks to evaluate the feasibility of a Abdominal Aortic Balloon Occlusion of the Aorta (AAJT-S) in exanguinating trauma patients with non-compressible truncal haemorrhage in the emergency room and the pre-hospital setting.
Detailed description
The study is designed as a prospective observational study to accomapany the impementation of this device in clinical routine. However, the device has already been used in the emergency room and AAJT-S application is no study specific intervention.
Interventions
None listed
Sponsors
Medical University of Graz
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* aged, or believed to be aged, 18 years or above, * confirmed or suspected life-threatening lower body trauma (i.e. signs of inadequate perfusion of tissues, tachycardia, hypotension, suspected blood loss) * is thought to benefit from trauma resuscitation with AAJT-S or REBOA zone III
Exclusion criteria
* suspected additional bleeding source proximal to the umbilicus, or * known or suspected pregnancy at presentation, or * known abdominal aortic aneurysm
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| effective placement of the device | 1 hour | cessation of bloodflow distal to the device |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 30-day mortality | 30 days | in-hospital |
| Complications | 90 days | Occurrence of complications of device application |
| Heart rate | 1 hour | Improvement (reduction) in beats/minute |
| Base excess | 1hour | Improvement (reduction) in mmol/l |
| Blood pressure (systolic and diastolic) | 1 hour | Improvement in mmHg |
Countries
Austria
Contacts
Primary ContactGabriel Honnef, MD, PhD
Outcome results
None listed