Post-Extraction Socket Healing, Ridge Preservation
Conditions
Keywords
ridge preservation, post-extraction healing, post-extraction resorption, dense polytetrafluoroethylene membrane, free gingival graft, platelet-rich plasma
Brief summary
The goal of this clinical trial is to learn if ridge preservation methods with dense polytetrafluoroethylene membranes, with d-PTFE membranes and platelet-rich plasma, and with free gingival grafts can reduce vertical resorption of the post-extraction socket walls. Researchers compared each experimental group to a control group (unassisted socket healing). Participants were randomly allocated to one of the four groups. Cone-beam computed tomography was performed after the procedure and 3 months post-operatively to evaluate the vertical socket wall resorption.
Interventions
PROCEDURERidge preservation technique
Tooth extraction, deperiostation of the buccal and oral marginal gingiva, placement of d-PTFE membranes and suturing.
PROCEDUREridge preservation
Tooth extraction, socket filling with PRP, deperiostation of the buccal and oral marginal gingiva, placement of d-PTFE membranes and suturing.
Sponsors
Medical University of Varna
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
1. Patients in the age group 18-65 years; 2. Patients in good general condition; 3. Patients requiring extraction of premolars or molars; 4. Patients in whom restoration of the missing tooth with a dental implant and/or prosthetic construction is planned; 5. Signed informed consent to participate in the study.
Exclusion criteria
1. Patients with contraindications for general surgical treatment: * patients with uncontrolled arterial hypertension; * patients with uncontrolled metabolic diseases; * patients with AMI in the last 6 months; * patients on hemodialysis treatment; * patients who underwent chemotherapy and/or radiotherapy in the last year; * patients on immunosuppressive therapy; * patients on anti-resorptive and anti-angiogenic therapy; * patients with concomitant acute diseases at the time of the study; * patients with proven psychiatric diseases; * pregnancy. 2. There are local contraindications: * insufficient volume of bone after the extraction to carry out RP; * acute inflammatory disease or tumor process in the area; 3. Lack of informed consent. 4. Lack of patient motivation for the treatment.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Vertical post-extraction resorption of the socket walls | 3 months | Each socket wall is measured using CBCT right after the extraction and after 3 months to assess the vertical resorption. |
Countries
Bulgaria
Outcome results
None listed