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The Beijing Adult Dry Eye Cohort Study

The Beijing Adult Dry Eye Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06621446
Acronym
ADEC
Enrollment
1200
Registered
2024-10-01
Start date
2023-07-15
Completion date
2025-08-31
Last updated
2024-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry Eye

Keywords

Prevalence, Incidence, Risk Factor, Dry Eye, Adult

Brief summary

To investigate the prevalence of dry eye in adults in Beijing, and explore the extremely dangerous factors of dry eye in adults in Beijing through two years follow-up, and establish a prediction model of dry eye; On this basis, the prevention and treatment strategy of dry eye disease suitable for Chinese people is put forward, and its actual effect is verified.

Detailed description

Specifically, it is planned to carry out cluster random sampling in Jianguomen community, Yongdingmenwai community, and Jiaodaokou community in Dongcheng District, Beijing, and select adults over the age of 18 to enter the queue for observation; In order to ensure the accuracy of the prevalence survey, people with mobility difficulties or mental problems are not excluded. The subjects will be examined by ophthalmology and OSDI questionnaire to determine whether these people have dry eyes. Then the prevalence of dry eye would be expolored. Then through one-year and two-year follow-up, the incidence would be explored.

Interventions

OTHERComprehensive intervention model

A dry eye intervention strategy: including health education, the use of eye drops, and regular review.

Sponsors

Beijing Tongren Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Aged 18 or above, resident population of sample community, able to complete dry eye examination, informed consent signed

Exclusion criteria

* Mental illness, mobility difficulties, can not participate in follow-up

Design outcomes

Primary

MeasureTime frameDescription
Incidence of Dry eyetwo yearsThe incidence of dry eye is the primary outcome, and will be calculated by number of newly developed dry eye cases divided by total number of those who didn't have dry eye in last year. The presence of dry eye will be measured relying on the following examinations: questionnaire, tear break-up time examination

Secondary

MeasureTime frameDescription
Prevalence of Dry Eyeone yearThe prevalence of dry eye is the secondary outcome. The prevalence will be defined as number of dry eye cases, divided by total participants. Dry eye will be measured relying on questionnaire and tear break-up time examination.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026