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Anomia Treatment Predictors

Predictors of Phonological-focused Anomia Treatment

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06619756
Enrollment
2
Registered
2024-10-01
Start date
2024-09-18
Completion date
2025-10-01
Last updated
2025-11-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anomia (Word-Finding Impairment), Aphasia

Keywords

anomia treatment, aphasia treatment

Brief summary

The goal of this clinical trial is to identify predictors of response to phonological-focused anomia treatment in people with aphasia. The main question it aims to answer is who responds to which type of anomia treatment. Researchers will compare Phonomotor Treatment and Phonological Components Analysis to see which treatment is more beneficial, and for whom. Participants will engage in both treatments over several months.

Detailed description

Participants will complete screening and characterization testing to determine eligibility for the study. Each treatment will be administered twice a week, for 10-15 sessions. Pre-treatment and post-treatment testing will also occur for each treatment. There will be a period of no treatment in between the first and second treatment blocks.

Interventions

BEHAVIORALPhonomotor Treatment (PMT)

Anomia treatment focuses on improving word-finding abilities. This intervention targets the phonology of words to improve word-finding.

BEHAVIORALPhonological Components Analysis (PCA)

Anomia treatment focuses on improving word-finding abilities. This intervention targets the phonology of words to improve word-finding.

Sponsors

State University of New York at Buffalo
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Chronic aphasia (6+ months) * Anomia * Sufficient auditory comprehension to follow task instructions * Phonologic impairment

Exclusion criteria

* Progressive neurological illness or disease, including dementia * Chronic medical illness that interferes with adherence to testing schedule * Severe, uncorrected vision or hearing impairment that interferes with task completion * Moderate-severe apraxia of speech or dysarthria that interferes with task completion

Design outcomes

Primary

MeasureTime frameDescription
Naming of Trained WordsPre-treatment and Immediately post-treatmentPicture naming of trained words

Secondary

MeasureTime frameDescription
Naming of Untrained WordsPre-treatment and Immediately post-treatmentPicture naming of untrained words
Standardized Assessment of Phonology in Aphasia (SAPA)Pre-treatment and Immediately post-treatmentThe SAPA assesses phonological processing abilities, including oral reading, rhyme judgments, minimal pair judgments, lexical decision, blending, and parsing.
Philadelphia Naming TestPre-treatment and Immediately post-treatmentThe short-form of the Philadelphia Naming Test is a picture naming test of items not seen during treatment.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026