Sepsis As a Cause of Death Among Elderly Cancer Patients

Sepsis As a Cause of Death Among Elderly Cancer Patients: an Updated SEER Database Analysis 2000-2021

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06619535

Enrollment

5239194

Registered

2024-10-01

Start date

2000-01-01

Completion date

2021-12-30

Last updated

2024-10-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer, Sepsis

Keywords

sepsis, Cancer, mortality, SMR, SEER

Brief summary

The goal of this retrospective study is to explore the association between sepsis and morality among the elderly cancer patients. Data were extracted from the Surveillance, Epidemiology and End Results( SEER) database using SEER\*stat software. The study included patients aged 65 years or more who were diagnosed with cancer from 2000 to 2021. The extracted data included age, race, marital status, sex, stage, surgery, chemotherapy and radiotherapy. Multiple primary session was used to calculate the standardized Mortality ratio (SMR) as Observed/Expected with excess risk/10,000 and significance was achieved at 0.05.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

Inclusion criteria

* cancer patients * age 65 year or more * latency exclusion period of 0 months.

Exclusion criteria

\- Death certificate only and autopsy only cases

Design outcomes

Primary

Measure	Time frame	Description
SMR for sepsis as a cause of death among elderly cancer patients	from Jan, 2000 till Dec, 2021	Patients were followed up from the time of diagnosis and the risk was assessed across different time intervals: 1 year, 5 years and +10 years after cancer diagnosis from 2000 to 2021

Countries

Egypt

Outcome results