Chronic Rhinosinusitis (CRS)
Conditions
Keywords
Dexamethasone Phonophoresis, Laser Acupuncture, Chronic Rhinosinusitis
Brief summary
This study is designed to provide a comprehensive overview of evidence concerning the efficacy and safety of dexamethasone phonophoresis and laser acupuncture for treatment of chronic rhinosinusitis.
Interventions
COMBINATION_PRODUCTDexamethasone phonophoresis
Ultrasound therapeutic device with the use of 0.4% Dexamethasone sodium phosphate gel for phonophoresis.
DEVICELaser Acupuncture
low level laser therapy placed in contact with the skin perpendicular over the body acupoints (LI 4) - (LI 20) - (EX- HN5) - (GV 20) - (GV 24) - (ST3) - (ST 7) in both sides and on (EX-HN3) acupoint,
OTHERTraditional medication
Each participant in this group receive the traditional medication.
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
30 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Age range between 30 to 50 years. * Male and female patients will participate in the study. * All patients have chronic rhinosinusitis, who are experiencing 12 weeks or longer of 2 or more of the following signs and symptoms: mucopurulent drainage (anterior, posterior, or both) nasal obstruction (congestion) facial pain-pressure-fullness, or decreased sense of smell • All patients enrolled in the study will have their informed consent.
Exclusion criteria
* Patients with metal implants (pacemakers, dental implants, or any other implants). * Patients with cancer, pregnancy or impaired vascular circulation. * Patients who suffer from mental or psychological disorders. * Patients with any systemic diseases that may interfere with the objectives of the study. * Patients with long-term use of corticosteroids or immunosuppressive agents. * Congenital defects on face and nose. * Fracture of nose or face. * Patients who are contraindicated for corticosteroids use in patient who will receive dexamethasone phonophoresis. * Allergic patients. * Pervious nasal surgery. * Patients with nasal septum deviation. * patients who had used antihistamines within 1 week, topical corticosteroids within2 weeks, systemic corticosteroids within 4 weeks, anti-cholinergic drugs within 3 days, antileukotriene drugs within 1 week, decongestants within 3 days, tricyclic antidepressants or phenothiazines within 2 weeks, non-steroidal analgesics within 2 weeks or any medication that may interfere with the objectives of the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Sino nasal Outcome Test 22 (SNOT-22) | one month | This is a Quality Of Life Questionnaire specifically designed for sinusitis patient. It consists of 22 item sinus specific question which has to be administered to the patient and the total sum of all the items will be recorded based on the severity of the patient's condition and the scores will be calculated |
| Computerized Tomography Scan | one month | CT scan will be used for assessment of mucosal thickening of maxillary sinuses, which is based on 0-3 system: 0 = clear, 1= mild or moderate mucosal thickening, 2 = severe mucosal thickening, 3 = total opacification |
Countries
Egypt
Outcome results
None listed