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PG Versus TG for Advanced PGC

Proximal Versus Total Gastrectomy for Advanced Proximal Gastric Cancer: A Retrospective Double-Center Propensity Score-Matched Cohort Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06614439
Enrollment
96
Registered
2024-09-26
Start date
2024-09-04
Completion date
2025-09-01
Last updated
2025-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrectomy, Gastric Adenocarcinoma

Brief summary

We conducted a retrospective study on patients with pathological stage II-III PGC who underwent PG or TG from 2013 to 2023. Propensity score-matching was applied to adjust for tumor size and stage between the PG and TG groups at a 1:1 ratio. We evaluated the procedural safety, oncological, and functional outcomes.

Interventions

proximal gastrectomy

total gastrectomy

Sponsors

National Taiwan University Hospital
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Proximal gastric adenocarcinoma after total or proximal gastrectomy.

Exclusion criteria

* Non-curative resections * Non-adenocarcinoma histology * Distally located tumors or middle/proximally located tumors for which distal margin could not be secured by PG * Remnant gastric cancer * Clinically T1N0 tumors smaller than 3 cm for which PG was clearly indicated

Design outcomes

Primary

MeasureTime frame
five-year overall survival5 years

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026