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Effects of Pharmacist-led Medication Reconciliation Services on Geriatric Patients

Effects of Pharmacist-led Medication Reconciliation Services on Geriatric Patients At a Leading Military Hospital in Jordan

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06610292
Enrollment
128
Registered
2024-09-24
Start date
2018-06-24
Completion date
2018-10-13
Last updated
2024-09-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Geriatric Patients, Medication Reconciliation At Discharge, Medication Reconcilitation Upon Hospital Admission, Pharmacist-led Medication Reconciliation

Keywords

Medication reconciliation, Geriatrics, Geriatric patients, Jordan, Tertiary military hospital, Pharmacist-led medication reconciliation

Brief summary

This study aims to assess the effects of Pharmacist-led medication reconciliation on hospitalized elderly patients aged above 65 at a leading tertiary military hospital in Jordan.

Detailed description

A four-month randomized controlled trial was conducted at King Hussein Medical Hospital (KHMH), one of the Royal Military Medical Services (RMS) tertiary hospitals located in central Amman. During the study period, 128 patients were selected using convenience sampling. Later, medication histories were compared between pre-admission and admission records to obtain the Best Possible Medication History (BPMH) and identify medication discrepancies, which were categorized as either intentional (documentation errors) or unintentional discrepancies. The already selected patients were randomly allocated into two groups (intervention and control groups). Then, Pharmacist-led medication reconciliation services were provided to the intervention group and standard care was provided to the control group. Also at discharge the number of medication discrepancies was documented. Linear regression analysis was performed to assess risk factors associated with the occurrence of unintentional discrepancies. Within 30 days post-discharge, patients were assessed for any hospital re-admissions, emergency department visits and medication-related side effects.

Interventions

OTHERPharmacist-led medication reconciliation services

Upon admission, information about patients Best Possible Medication History (BPMH) was extracted. Information on current medications, both regular and as-needed, was also recorded. All data were cross-referenced with the electronic records and verified through patients or caregivers interviews to create a comprehensive medication list. Then, comparison was conducted between standard care medication list and Pharmacist-led medication reconciliation list to identify any possible medication discrepancies. Also, during hospital stay and upon discharge emerging medication discrepancies were assessed and resolved. Moreover, the impacts on healthcare resources utilization within 30 days post-discharge was measured. This includes evaluating hospital re-admissions, emergency department visits, and the occurrence of any adverse drug events (ADEs).

Sponsors

Jordanian Royal Medical Services
CollaboratorOTHER
Royal Medical Services, Jordanian Armed Forces
CollaboratorOTHER
University of Jordan
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE (Caregiver)

Eligibility

Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Newly admitted patient within no more than 24 hours and anticipated to stay in the hospital for more than 48 hours. * Geriatrics patients defined as those aged (≥65 years) (Orimo et al., 2006). * Prescribed at least one chronic medication prior to the study admission.

Exclusion criteria

* Patient admitted to the critical care or isolation units or in unconscious or comatose states. * Patients if they were discharged against medical advice.

Design outcomes

Primary

MeasureTime frameDescription
Describing prevalence and nature of medication discrepancies in elderly patients and investigating contributing factors to medication discrepancies.Up to 20 weeksLinear regression analysis was performed to assess risk factors associated with the occurrence of medication discrepancies in elderly patients.
Analysis of the effects of Pharmacist-led medication reconciliation services on resolving medication discrepancies upon dischargeUp to 16 weeksNumber of resolved medication discrepancies was documented upon discharge after providing pharmacist-led medication reconciliation services.
Evaluating the impacts of Pharmacist-led medication reconciliation services on hospital re-admissions within 30 days of dischargeUp to 20 weeksElderly patients were assessed for number of hospital re-admissions within 30 days of discharge at control and intervention groups.
Evaluating the impacts of Pharmacist-led medication reconciliation services on emergency department visits within 30 days of dischargeUp to 20 weeksElderly patients were assessed for number of emergency department visits within 30 days of discharge at control and intervention groups.
Evaluating the impacts of Pharmacist-led medication reconciliation services on medications side effects within 30 days of dischargeUp to 20 weeksElderly patients were assessed for incidence of medications side effects within 30 days of discharge at control and intervention groups.

Countries

Jordan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026