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Combined Effects of Isometric Wall Squats and High Intensity Interval Training on Rate Pressure Product in Normotensive and Pre-hypertensive Sedentary Adults

Combined Effects of Isometric Wall Squats and High Intensity Interval Training on Rate Pressure Product in Normotensive and Pre-hypertensive Sedentary Adults

Status
Active, not recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06610006
Enrollment
44
Registered
2024-09-24
Start date
2024-06-10
Completion date
2024-12-15
Last updated
2024-09-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pre Hypertension

Brief summary

Hypertension is leading yet preventable risk factor for cardiovascular disease and all-cause mortality worldwide. Prehypertension identifies those at high risk of developing HTN, prompting intervention to prevent or delay the onset of the disease. High intensity interval training (HIIT) is a time efficient mode of training with established benefits, while Isometric wall squats (IWS) also provide a range of proven benefits and advantages, but their combined effect on BP measures is yet to be determined.Hence the objective of this study is to compare the effects of isometric wall squats along with high intensity interval training versus high intensity interval training alone on rate pressure product, SBP and DBP, heart rate and anthropometric measures in normotensive and pre-hypertensive sedentary adults

Detailed description

Pre-Hypertension is not a disease itself rather it categorizes those who are at the risk of developing hypertension in future. By targeting pre-hypertensive and normotensive individuals we are focusing on preventive measures, potentially reducing incidence of HTN and cardiovascular conditions in future. If found effective, this study can help in providing training protocols while also decreasing the risk of hypertension in future.A total of 15 sessions of high intensity interval training alone in one group and combination of high intensity interval and isometric wall squat in other group, for thrice a week on alternative days for 5 consecutive weeks will be given.

Interventions

PROCEDUREHigh Intensity Interval Training (HIIT)

High intensity interval training on treadmill with moderate intensity (40-60%HRR) in week 1 to achieve the baseline fitness level and from week 2 to 5 they will progress to high intensity with setting the lower target HR 40-60%HRR and upper target HR 80-85%HRR with 1:4 work to rest ratio followed by 5-7 min of cool-down period..A total of 15 sessions of high intensity interval training alone , for thrice a week on alternative days for 5 consecutive weeks will be given. Warm-up session consisting of stretching exercises prior to intervention and cool down session after intervention will also be done and vitals before and after the session will be taken.

For isometric wall squat, each training session will be composed of 4 × 2-min bouts of IWS followed by 2-min rest periods. In first week, participants will do squat training or there will be a protocol for selecting exercise intensity in which participants will be given 30-s to perform a wall squat to select a position that they predict would elicit an target RPE score by varying the squat height. Based on the final squat height and RPE score, after bout 4, participants will be given a starting squat height for training session 1 and will then be progressed in each week

Sponsors

Foundation University Islamabad
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Intervention model description

This is a randomized controlled trial having two groups. One group(interventional group) will be doing High Intensity Training (HIIT) and Isometric Wall Squat and the other group (control group) will be doing High intensity Interval Training (HIIT).

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

* Both male and female adults aged 18-45 years. * Participants lying in Low PA (inactive) category on basis of IPAQ. * Pre-hypertensive adults: * SBP- 120 mmHg or more and \<140 mmHg * DBP of 80 mmHg or more and \< 90 mmHg. * Normotensive adults: SBP \< 120 mmHg and DBP \< 80 mmHg.

Exclusion criteria

* Diagnosed with any current infections. * Subjects with any diagnosed cardiovascular or respiratory conditions. * Subjects with diagnosed musculoskeletal or neurological conditions which hinder participation in physical activity program. * Active Smokers * Those with any contraindication to exercise testing or training. * Pregnant females

Design outcomes

Primary

MeasureTime frameDescription
Rate Pressure Product5 weeksMeasured by multiplying Heart Rate and Systolic Blood Pressure
Blood Pressure(SBP and DBP)5 weeksEvaluation will be done using sphygmomanometer
Heart rate5 weeksHeart Rate will be measured using pulse oximeter.
Anthropometric Measures Waist circumference5 weeksMeasuring Tape will be used to measure Waist circumference
Anthropometric Measures hip circumference5 weeksMeasuring Tape will be used to measure hip circumference
Anthropometric Measures Waist to hip ratio5 weeksRatio of waist circumference and hip circumference
BMI5 weeksBody mass index ratio of weight and height

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026