Pain, Postoperative, Post Operative Swelling, Soft Tissue Healing, Trismus
Conditions
Keywords
prf, extraction socket, post operative complications, wisdom tooth extractions, surgical extractions
Brief summary
As post-operative pain, infection inflammation and infections are the main complications after the surgical extraction of the lower third molar the aim of this study is to compare the healing effects of PRF administered postoperatively
Detailed description
PRF will be randomly administered into one group of patients undergoing any extractions group A (Right after the extraction) Group B will be a control group in which extraction sockets will be left to heal with the natural blood clot. Consenting patients will be assigned into groups randomly and not informed which group they were placed into. The PRF will be administered obtained from a tube of 10 ml blood and no material will be placed in the control group. The progress of healing and post-operative complications will be tracked over a period of 7 days with patients being called for follow-up on days 3, 5 and 7. Their post-operative complications will be checked at every subsequent visit and noted in the questionnaire. The Questionnaire is structured and will be interviewer-administered. It will comprise of basic bio-demographic data (such as name, age, sex, etc) and 3 closed-ended questions related to post-operative complications following the extraction
Interventions
PROCEDUREapplication of PRF
PRF will be randomly administered into one group of patients undergoing any extractions group A (Right after the extraction) Group B will be a control group in which extraction sockets will be left to heal with the natural blood clot. Consenting patients will be assigned into groups randomly and not informed which group they were placed into. The PRF will be administered obtained from a tube of 10 ml blood and no material will be placed in the control group. The progress of healing and post-operative complications will be tracked over a period of 7 days with patients being called for follow-up on days 3, 5 and 7
PROCEDUREapplication of conventional surgicel
it will be a control group in which extraction sockets will be left to heal with the natural blood clot.
Sponsors
Dow University of Health Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
1. Both male and female patients 2. Patients that give their consent to the use of their information and to the administration of the drug will be the participants of the study. 3. Patients with 3rd molar impactions 4. Absence of systemic diseases 5. age ⩾18 years and the ability to cooperate with the requirements of the study protocol.
Exclusion criteria
1. Medically compromised patients. 2. Immunocompromised patients. 3. Patients that do not consent. 4. Patients that are below the age of 17. 5. Patients that are pregnant. 6. Fully erupted molars will be excluded. smokers (> 5 a day) will be excluded as well.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain | 7 days | Post-operative pain will be measured using a visual analog scale in both groups i.e. conventional therapy group and PRF group on the 1st, 3rd and 7th post operative day. |
| Post operative Swelling | 7 days | Post operative swelling will be measured in terms of metric calculation (centimeters) in 2 sites i.e: 1. From the tragus of the ear to angle of mouth and 2. From lateral canthus of eye to angle of mandible on the 3rd and 7th post operative day. |
| Trismus- Post surgical limitation in mouth opening | 7 days | Trismus will be measured as the distance in (cm) between the edges of the maxillary and mandibular central incisors post surgically on the 3rd and 7th post operative day. |
| Wound/ extraction socket healing | 7 days | The wound healing of the extraction socket of mandibular wisdom teeth will be assessed according to Landry's criteria on the 7th post operative day. |
Countries
Pakistan
Outcome results
None listed