Autogenous Dentin Graft
Conditions
Keywords
dentin graft, tooth graft
Brief summary
Randomized clinical and radiographic trial
Detailed description
Evaluation of Autogenous Dentin Graft versus Demineralized Freeze-Dried Bone Allograft in the Treatment of Class ΙΙ and ΙΙΙ Mandibular Furcation Defects
Interventions
PROCEDURE(guided tissue regeneration)
Randomized clinical and radiographic trial
Sponsors
Tanta University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Intervention model description
2 groups with 2 subgroups, each subgroup receive either ADG or DFDBA
Eligibility
Sex/Gender
ALL
Age
35 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
\- Presence of class II and/or ΙΙΙ furcation defects in mandibular first or second molars according to criteria outlined by Hamp et. al. 1975. * Horizontal probing depth ≥3 mm using Naber's probe. * Clinical attachment level ≥3 mm measured from cemento-enamel junction (CEJ) till the deepest probing depth. * Evidence of radiolucency in the furcation area on panoramic radiograph. * Patients who will be assigned for groups (I and II) should present with teeth required for extraction due to advanced periodontal bone loss or other indications such as hopeless wisdom teeth or orthodontic indications or unrestorable fractured teeth as a source for autogenous dentin graft (ADG).
Exclusion criteria
* Medically compromised patients and systemic conditions precluding periodontal surgery. * Mandibular first or second molars with root caries or endodontic treatment. * Smokers, diabetics, pregnant or lactating women. * History of chemotherapy, radiotherapy in head and/or neck region. * Bisphosphonate therapy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Probing pocket depth | Measured at baseline, 6 months and 12 months | According to Ramfjord, clinical parameter measured by UNC periodontal probe from a fixed point to the deepest probing depth. Using stent to standardize the measurements. |
| Clinical attachment level | Measured at baseline, 6 months and 12 months | According to Ramfjord, clinical parameter measured by a Naber's probe. Using stent to standard measurements. |
| Bleeding on probing | Measured at baseline, 6 months and 12 months | According to Ramfjord, the bleeding at each site observed after probing and recorded positive if bleeding was observed within 30 seconds, if not was recorded as negative. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Radiographic outcome | measured at baseline and 1 year follow up | Using CBCT software to analyse furcation volume |
Countries
Egypt
Outcome results
None listed