Infertility (IVF Patients), IVF, Ovarian Aging
Conditions
Brief summary
The goal of this observational study is to learn about egg physiology in humans. The main question it aims to answer is if there is an association between egg physiology and egg quality. Discarded, unfertilised eggs and follicular fluid collected during routine egg retrieval from participants undergoing in vitro fertilisation (IVF) as part of their regular medical care along with information from participants' electronic medical records will be collected and analysed.
Interventions
OTHERInformative Appointment
The only intervention involving the participants is non-clinical, which is an extra 30-minute informative telephone appointment added to the standard care consultation schedule of interested IVF patients where they will be presented with a digital consent PDF form to sign by a study nurse or clinically trained research personnel. Participants will be in the study for 24-30 months. During this time their discarded, unfertilised oocytes and follicular fluid collected during routine oocyte retrieval along with information from their electronic medical records will be collected and analysed.
Sponsors
Ovom Care GmbH
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Healthy volunteers
No
Inclusion criteria
* Undergoing in vitro fertilisation treatment or egg freezing
Exclusion criteria
* No discarded, unfertilised eggs for collection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mitochondrial physiology in the oocytes | Baseline time of observation which lasts between 1 and 5 hours |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of oocyte mitochondrial physiology results to clinical outcomes to assess correlation (or lack thereof) | As the data becomes available over the course of the participants' medical treatment. E.g. From enrolment until birth of an infant |
Countries
United Kingdom
Outcome results
None listed