Hyperspectral Imaging, Liver Transplantation
Conditions
Keywords
liver transplantation, Hyperspectral Imaging, Evaluation of donor liver, Early Complications
Brief summary
Based on hyperspectral imaging equipment, this project collected hyperspectral imaging data of donor livers, analyzed various parameters, investigated the detection capability of hyperspectral imaging for assessing donor liver quality, gathered patient prognosis information, examined the correlation between early postoperative complications and hyperspectral imaging data, and explored characteristic parameters for evaluating donor liver quality using hyperspectral imaging technology. The occurrence of early complications was predicted.
Detailed description
Hyperspectral imaging (HSI) is an advanced optical technology that combines spectroscopy and imaging, providing a non-destructive approach for clinical diagnosis. In recent years, hyperspectral imaging has emerged as a prominent research topic in the field of applied medicine. Liver transplantation is considered the most effective treatment for end-stage liver disease; however, the scarcity of donor livers and the growing number of patients awaiting transplantation pose significant challenges to global organ transplantation. The evaluation of donor livers has always been a focal point in liver transplantation. Currently, clinical evaluation relies heavily on subjective judgment by transplant physicians based on general appearance and touch assessments, along with clinical examinations and pathological biopsy results. Nevertheless, studies have demonstrated that these methods are not entirely reliable for assessing liver quality. Therefore, it is crucial to identify additional evaluation parameters and establish a convenient, reliable, and non-invasive method to assess donor liver quality. This study aims to analyze hyperspectral imaging data alongside clinical test data and recipient complications occurring between June 2022 to June 2024 to evaluate the quality of donor livers using hyperspectral imaging technology while exploring potential evaluation parameters.
Interventions
DEVICEThe study was retrospective and did not involve the application of interventions
The study was retrospective and did not involve the application of interventions
Sponsors
First Affiliated Hospital Xi'an Jiaotong University
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
1. Recipients ranged in age from 18 to 65 2. Donor age ≥ 18 years
Exclusion criteria
1. Recipients are younger than 18 years or older than 65 years 2. Donor younger than 18 years 3. Secondary liver transplantation. 4. Multiple organ transplantation.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hyperspectral imaging to assess ischemia-reperfusion injury in liver grafts | From June 1,2022 to June 30,2024 | Assessment of severity of ischemia-reperfusion injury of donor liver grafts by hyperspectral imaging |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Assessment of fatty liver graft using hyperspectral imaging | From June 1,2022 to June 30,2024 | Assessing the severity of fatty liver using Hyperspectral Imaging |
| Hyperspectral imaging predicts early serologic markers of liver function and inflammatory factors | From June 1,2022 to June 30,2024 | — |
| Assessing early allograft dysfunction after liver transplantation using hyperspectral imaging | From June 1,2022 to June 30,2024 | — |
Countries
China
Outcome results
None listed