Sarcopenia in Elderly
Conditions
Keywords
Resistance Exercise, Creatine, Whey Protein, Strength, Lean Mass
Brief summary
The primary purpose of this research is to compare the effects of creatine monohydrate and/or whey protein supplementation during the first 10 weeks of a 20-week resistance-band training program on measures of body composition (whole-body lean tissue mass, total body water), arm and leg muscle thickness, upper- and lower-body muscle performance (i.e., strength, endurance) and functional ability (walking speed, balance). A secondary purpose of this research is to examine the effects of supplementation cessation (i.e., no creatine and/or whey protein supplementation) during the final 10 weeks of the 20-week resistance-band training program on these measures.
Detailed description
Sarcopenia, characterized by the age-related reduction in strength, muscle mass, and physical function, decreases the ability to perform activities of daily living. Physical inactivity and inadequate nutrition are contributing factors to the development of sarcopenia. Resistance training is a safe, viable and effective intervention which increases measures of muscle and bone mass, muscle performance (i.e., strength, endurance) and functional ability in older adults. However, older adults indicate that high costs and difficulty finding training programming and/or facilities are barriers to participating in resistance training. Home-based resistance-band training is safe, effective and serves as a viable alternative to traditional resistance training (i.e., involving free-weights and machine-based equipment). From a healthy aging perspective, resistance-band training elicits similar improvements in strength (primary indicator of sarcopenia) and functional ability compared to traditional resistance training in older adults. In addition to resistance training (involving resistance-bands), creatine and whey protein supplementations have also been shown to have favorable effects on measures of muscle, bone and functional ability in older adults. However, no study has examined the effects of resistance-band training and creatine and whey protein supplementation in older adults.
Interventions
DIETARY_SUPPLEMENTCreatine Whey Protein
3 grams creatine + 30 grams whey protein
DIETARY_SUPPLEMENTWhey Protein
30 grams Whey Protein
Sponsors
University of Regina
Iovate Health Sciences International Inc
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Untrained (defined as those performing ≤ 1 resistance training session per week for ≥ 6 weeks prior to the start of the study)
Exclusion criteria
* Taking creatine monohydrate within 30 days prior to the start of the study * Currently ingesting whey protein * Have pre-existing allergies to latex, fruit, dairy, nuts, seafood and mustard
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Whole-body lean mass (kg) | baseline, week 10, week 20 | Bioelectrical impedance analysis |
| Strength (kg) | baseline, week 10, week 20 | 1-repetition maximum leg press and chest press |
| Endurance (number of repetitions to fatigue) | baseline, week 10, week 20 | Leg press and chest press |
| Balance (Centre of Pressure) | baseline, week 10, week 20 | Force Plate |
| Hydration (kg) | baseline, week 10, week 20 | Bioelectrical impedance analysis |
| Gait Speed (meters) | baseline, week 10, week 20 | Walking distance |
| Muscle Hypertrophy (cm) | baseline, week 10, week 20 | B-mode ultrasound |
Countries
Canada
Contacts
Primary ContactDarren Candow
Outcome results
None listed