Improve Muscle Performance in Young Adults
Conditions
Brief summary
The purpose is to compare the effects of bolus ingestion (5 grams) vs. intermittent ingestion (2 x 2.5 grams) of creatine supplementation vs. placebo for 21 days on measures of body composition (lean tissue mass-indicator of muscle mass, total body water) and muscle performance (i.e., power, strength, endurance).
Detailed description
Creatine is a naturally occurring compound produced in the liver and brain. Creatine can also be found in food products such as red meat and seafood or through commercially available manufactured creatine products (i.e. creatine supplementation). Evidence-based research shows that creatine supplementation improves measures of body composition and muscle performance. However, the optimal creatine supplementation protocol to achieve these benefits is unknown.
Interventions
DIETARY_SUPPLEMENTCreatine
Creatine monohydrate
DIETARY_SUPPLEMENTPlacebo
Maltodextrin
Sponsors
University of Regina
Iovate Health Sciences International Inc
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 39 Years
Healthy volunteers
Yes
Inclusion criteria
* if you are 18-39 years of age * if you have not been performing resistance training for at least 4 weeks prior to the start of the study.
Exclusion criteria
* if you are pregnant or nursing * have taken creatine monohydrate within 30 days prior to the start of the study * if you have pre-existing allergies to the placebo (corn-starch maltodextrin)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Whole-body lean mass (kg) | baseline, day 21 | Bioelectrical impedance analysis |
| Strength | baseline, day 21 | 1-repetition maximum leg press and chest press (kg) |
| Endurance | baseline, day 21 | Repetitions to fatigue for leg press and chest press (total number) |
| Hydration | baseline, day 21 | Total body water (kg) using bioelectrical impedance analysis |
| Power | baseline, day 21 | Vertical Jump (cm) |
Countries
Canada
Contacts
Primary ContactDarren Candow
Outcome results
None listed