Prostate Cancer
Conditions
Keywords
PET/MR, Prostate cancer, Biochemical recurrence, Multicenter
Brief summary
The purpose of this study is to investigate the predictive value of preoperative 18F-PSMA-1007 PET/MR in the predictive effect of biological recurrence (BCR) after radical prostatectomy (RP) for localized prostate cancer (PCa).
Detailed description
Construct a predictive model for biochemical recurrence (BCR) in patients after radical prostatectomy using imaging parameters from preoperative 18F-PSMA-1007 PET/MRI, and compare the predictive performance of this model with existing clinical models. Data from three centers will be collected, with datasets from two centers used as the training set for the selection of predictive factors and model construction, while the dataset from the remaining center will serve as the validation set to assess the predictive performance of the model for BCR after prostatectomy.
Interventions
OTHERObserve
Ruijin
Sponsors
Ruijin Hospital
Study design
Observational model
OTHER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Age ≥ 18 years 2. Histologically confirmed prostate cancer without other types of malignancy -
Exclusion criteria
1.Surgery or endocrine therapy is performed prior to the examination \-
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 18F-PSMA-1007 PET/MR image parameters | Before surgery |
Secondary
| Measure | Time frame |
|---|---|
| Biochemical recurrence-free survival time | 3 years |
Countries
China
Outcome results
None listed