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Phenotypes of Preschool Wheezing Among Children Attending Sohag University Hospital

Phenotypes of Preschool Wheezing Among Children Attending Sohag University Hospital

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06603584
Enrollment
100
Registered
2024-09-19
Start date
2024-06-04
Completion date
2025-04-04
Last updated
2024-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wheezing

Brief summary

Wheezing in preschool children is very common, with a wide differential diagnosis. It is essential to be sure of the exact sound that parents are describing; the term 'wheeze' is often applied to non-specific sound.Approximately one-third of children are diagnosed with wheeze in the first 3 years of life, making wheeze one of the commonest respiratory symptoms.The differential diagnosis of wheeze is wide, and different management strategies are needed depending on the underlying phenotype. The word 'wheeze' is used to describe many different sounds. That can be heard by both clincians and parent. Even if true wheeze is heard, this should not be automatically assumed to be due to bronchospasm. Airway narrowing by mucus will produce true wheeze but does not respond to bronchodilators. Similarly, airway malacia, either related to intrinsic airway wall defects or loss of alveolar tethering points, are also causes of bronchodilatorunresponsive wheeze; indeed, bronchodilators, by reducing airway smooth muscle tone, may actually worsen airway narrowing.

Interventions

RADIATIONChest x- Rays

prebronchial Thicknening - Right upper lobe Patches suggesting Aspiration -Collapsing lobe

Sponsors

Sohag University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
2 Years to 6 Years
Healthy volunteers
No

Inclusion criteria

* patients from the age of one to five years with recurrent wheezing

Exclusion criteria

* Children above 5 years and below one year old. * Failure to obtain informed consent. * Children below 6 years with chest diseases other than wheezing

Design outcomes

Primary

MeasureTime frameDescription
Forced Expiratory Volume6 monthsChanges in Forced Expiratory Volume in bronchial Asthmatic Patient

Countries

Egypt

Contacts

Primary ContactAmr A Farghal, resident
amrahmed@med.sohag.edu.eg01020479524
Backup ContactMostfa A Mohammed, assistant professor

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026