Pediatric Liver Transplantation, Postoperative Acute Kidney Injury
Conditions
Brief summary
Acute kidney injury (AKI) is a common complication after pediatric liver transplantation (PLT), and renal impairment after LT has proven to be related with increased graft failure and mortality. The recovery mode of kidney injury after PLT has not been systematically studied. Therefore, in this study the investigators aimed to systematically evaluate prognosis of AKI after PLT, combine the recovery mode of AKI with related risk factors, and establish a relationship between AKI and CKD.
Interventions
OTHERNo Intervention: Observational Cohort
no intervention
Sponsors
Tianjin First Central Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 18 Years
Healthy volunteers
No
Inclusion criteria
* Patients who received a liver transplant for the first time. * Patients who were younger than 18 years of age at the time of transplant.
Exclusion criteria
* Patients with incomplete clinical data. * Patients with less than 5 years of follow-up. * Patients who have combined multiple solid organ transplants. * Patients with preoperative renal impairment (eGFR\<60ml/min/1.73 m2 or prior renal replacement therapy).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Graft survival | Based on the most recent follow-up before December 31, 2023. The investigators collected clinical data of patients from 2014 to 2018, and followed enrolled participants until at least 5 years after surgery | Loss of graft is defined as patient death or secondary transplantation |
Countries
China
Outcome results
None listed