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Trends of Patient-reported Outcome Measures (PROMs) in Multimorbid Medical Patients Hospitalized for an Acute Illness

Trends of Patient-reported Outcome Measures (PROMs) in Multimorbid Medical Patients Hospitalized for an Acute Illness

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06597318
Acronym
TRADUCE
Enrollment
1000
Registered
2024-09-19
Start date
2023-07-01
Completion date
2025-10-01
Last updated
2024-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Internal Medicine, PREM, PROM, Quality of Care

Brief summary

currently, PROMs and PREMs are not routinely collected and compared among medical inpatients of Swiss university hospitals, nor is a standard set of PROMs and PREMs available for use in Swiss hospitals. The project aims to examine trends in patient-reported outcomes (PROMs), including symptoms, quality of life, and distress, in multimorbid hospitalized patients from admission to 30 days post-discharge. It will also investigate whether PROMs at discharge are linked to the risk of readmission or emergency visits and explore how these outcomes differ in patients who receive low-value care. Additionally, the project will assess the relationship between patient-reported experiences (PREMs) and the provision of low-value care during the hospital stay.

Interventions

OTHERHospitalization

The investigators collect PROMs amongst up to 1000 patients in general internal medicine divisions of all five Swiss university hospitals

Sponsors

Insel Gruppe AG, University Hospital Bern
CollaboratorOTHER
University Hospital, Geneva
CollaboratorOTHER
University Hospital, Zürich
CollaboratorOTHER
University Hospital, Basel, Switzerland
CollaboratorOTHER
University of Lausanne Hospitals
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* eligible for the LUCID registry (CER-VD AO\_2023-00029) \[Age ≥ 18 years, hospitalized in one of the five participating university hospitals (Geneva, Lausanne, Bern, Zürich, Basel), after 01.01.2014, and admitted to general internal medicine wards * Multimorbid patients (2 or more chronic diseases, defined as chronic conditions defined by international classification of diseases, 10th revision, codes with an estimated expected duration of at least 6 months or based on a clinical decision. * Acute illness * Signature of study specific informed consent

Exclusion criteria

* Not able to speak French, German or English * Foreseen length of stay of less than 4 days (estimated by study collaborators) * Prior inclusion in the TRADUCE study * Incapacity of discernment, i.e. cognitive impairment which could interfere with the ability to fill in PROMs tools

Design outcomes

Primary

MeasureTime frameDescription
Correlation of PROMS with the risk of readmissionDay 1, Day 3, at the day of discharge (approximately day 8) and Day 30 after discharge from HospitalThe primary objective of the project is to explore trends in PROMs (using the Edmonton Symptom Assessment System (ESAS-r), the EQ-5D-5L index,45 and the National Comprehensive Cancer Network (NCCN) distress thermometer) of multimorbid medical hospitalized patients, from admission until 30-days post-discharge. The patients-reported outcomes will consist of patients-reported symptoms, quality of life and distress

Secondary

MeasureTime frameDescription
Correlation of PROMs at discharge and risk of hospital readmission or ED visitsDay 30 after discharge from hospitalassess whether PROMs ((using the Edmonton Symptom Assessment System (ESAS-r), the EQ-5D-5L index,45 and the National Comprehensive Cancer Network (NCCN) distress thermometer) at discharge are associated with the risk of hospital readmission or of emergency department visit within the next 30 days;
Exploration of PROMs in patients who receive low-value careDay 1, Day 3, at the day of discharge (approximately day 8) and Day 30 after discharge from Hospitalexplore whether PROMs ((using the Edmonton Symptom Assessment System (ESAS-r), the EQ-5D-5L index,45 and the National Comprehensive Cancer Network (NCCN) distress thermometer) trends vary in patients who do or do not receive low value care (LVC);
Explore PREMsSince 24 hours after beginning of the hospitalization up to Discharge from Hospital (approximately day 8)Explore information on Patient Reported Experiences Measures (PREMs) using a qualitative questionnaire during patients' stay at the hospital, and whether there is a correlation between the provision of LVC and qualitative analysis of PREMs

Countries

Switzerland

Contacts

Primary ContactMarie Méan, MD
marie.mean@chuv.ch+41 213141111

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026