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Risk Factors and Deep Learning Model for CI-AKI

Investigation and Early Risk Prediction of Acute Kidney Injury Caused by Iodinated Contrast Agents: Development of CI-AKIDPi Model Based on Interpretable Deep Learning

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06596785
Enrollment
2000
Registered
2024-09-19
Start date
2024-06-01
Completion date
2025-06-01
Last updated
2024-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

AKI - Acute Kidney Injury

Brief summary

Contrast-associated acute kidney injury (CI-AKI) is a sudden and significant decline in renal function resulting from the use of a contrast agent.

Detailed description

Contrast-associated acute kidney injury (CI-AKI) is a sudden and significant decline in renal function resulting from the use of a contrast agent. Despite the frequent use of iodinated contrast agents in medical investigations, predictive models for CI-AKI are scarce. This study aimed to construct and validate interpretable deep learning models for the early risk prediction of acute kidney injury (AKI) associated with iodinated contrast agents.

Interventions

None listed

Sponsors

Xiao Li,MD
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* patients who received iodinated contrast agents during hospitalization * age ≥ 18 years * hospitalization length ≥ 48 hours * at least two serum creatinine tests during hospitalization

Exclusion criteria

* patients with stage 4 or 5 chronic kidney disease prior to admission * patients undergoing hemodialysis, hemofiltration or peritoneal before admission * a history of nephrectomy or kidney transplantation during hospitalization * incomplete clinical information * Serum creatinine always ≤ 40 μmol/L during hospitalization

Design outcomes

Primary

MeasureTime frameDescription
AKICompleted through study, up to half a yearDuring the patient's hospitalization, acute kidney injury occurred after the use of Iodinated contrast media

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026