Evaluation of Retinal Vascular Density in High Myopia Without Pathological Myopic Maculopathy Using OCTA .

Status

Recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06596408

Enrollment

Registered

2024-09-19

Start date

2024-09-11

Completion date

2025-10-31

Last updated

2024-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

High Myopia

Brief summary

Study aiming to evaluate Macular Vascular Density in High Myopes without pathological myopic maculopathy in outpatient clinic in Sohag teaching hospital using OCTA .

Detailed description

Study Design : This is a cross sectional observational study , of about 50 patients attending ophthalmology outpatient clinic at Sohag Teaching Hospital . Inclusion criteria : All myopic patients with axial high myopia (-6 spherical refractive error or more) attending the ophthalmology outpatient clinic . Exclusion criteria : The exclusion criteria will include : * History of other any ocular diseases , systemic diseases that may affect the ocular circulation . * Previous intraocular surgery or ocular injury . * Any patient with pathological myopic maculopathy (epiretinal membrane, foveoschisis, macular holes, lamellar holes, Lacquers cracks, choroidal neovascularization and retinal atrophy ) .

Interventions

OTHERoptical coherence tomography angiography

OCTA will be used to evaluate the macular vascular density and to exclude patients with pathological myopic maculopathy

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

OTHER

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

15 Years to No maximum

Healthy volunteers

Inclusion criteria

wil include : * All myopic patients with axial high myopia (-6 spherical refractive error or more) of different age groups .

Exclusion criteria

will include : * -History of other any ocular diseases , systemic diseases that may affect the ocular circulation . * Previous intraocular surgery or ocular injury . * Any patient with pathological myopic maculopathy as epiretinal membrane, foveoschisis, macular holes, lamellar holes, Lacquers cracks, choroidal neovascularization and retinal atrophy .

Design outcomes

Primary

Measure	Time frame	Description
Outcome of evaluation of vascular density in high myopes	6 month	Correlation between macular vascular density in high myopes and their : Uncorrected visual acuity in diopters . Best corrected visual acuity in diopters . Spherical equivalent refraction that measured through this equivalent (spherical error + 1/2 cylindrical error ) . Central macular thickness in micrometers . To see how does ischemia affects vision in high myopes .

Countries

Egypt

Contacts

Primary ContactSara Magdy Mohammed, Master degree

saramagdy@med.sohag.edu.eg00201096507733

Backup ContactIslam Awny Ahmed, Ass. Prof

00201006429637

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026