Skip to content

Evaluation of Maternal Mental Health Following Ultrasonography Detection of Fetal Congenital Anomalies

Evaluation of Maternal Mental Health Following Ultrasonography Detection of Fetal Congenital Anomalies

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06594952
Enrollment
120
Registered
2024-09-19
Start date
2024-10-01
Completion date
2025-09-01
Last updated
2024-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mental Disorder

Brief summary

The purpose of this study is to evaluate maternal mental health during antenatal and postnatal periods after Ultrasonography diagnosis of fetal anomalies.

Detailed description

Fetal congenital anomalies are responsible for a great deal of abortions in desired pregnancies . In clinical practice, prenatal screening programs in 1st and 2nd trimester target both chromosomal and structural abnormalities. These congenital anomalies are classified as minor and major anomalies than may lead to death or stillbirth . Half of all anomalies are detectable during weeks 18-22 of pregnancy. Due to the advances occurring in Ultrasonography and screening paradigms, the rate of diagnosed anomalies is increasing dramatically which in turn leading to psychological distress in the pregnant mother. Receiving a diagnosis of fetal anomaly is a highly stressful and potentially traumatic event that can elicit immediate feelings of grief, loss, anger, depression, and anxiety. However, the foreknowledge of a fetal anomaly during pregnancy may enable the mother to prepare mentally resulting in reduced maternal stress after delivery. The American College of Medical Genetics recommends underscoring the importance of psychological assessment and substantive communication with parents facing a prenatal diagnosis of fetal anomaly. Despite the accessibility of establishing the significant symptoms of maternal psychological distress, the evidence on the definite nature of this distress in consideration to other life stressors and an accurate the prediction of women vulnerability in the critical period have not been clear yet due to many methodological issues. Identification of women at highest risk for poor adaptation to the diagnosis may allow for targeted psychological support services for those most vulnerable.

Interventions

OTHERQuestionnaire and Physical Exam

Diagnosis of Anxiety using the state-trait anxiety inventory scale (STAI). Depression using Edinburgh Postnatal Depression Scale (EPDS) * Coping using the Brief Coping Scale * Socioeconomic using the Socioeconomic Scale of Egypt * Personality using the short-form Eysenck Personality Questionnaire-Revised (EPQ-R) * Behaviour using Impact of Erect Scale (IES-22)

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Pregnant women with confirmed pregnancy with viable fetus (whether singleton or multiple) * Fetal anomaly should be diagnosed with ultrasonography (whether minor or major) after 12 weeks of gestational age

Exclusion criteria

\- Women with history of psychiatric disorders.

Design outcomes

Primary

MeasureTime frameDescription
Difference in anxiety scores between the study groups4 weeksusing the state-trait anxiety inventory scale (STAI).

Secondary

MeasureTime frameDescription
Difference in Depression scores between the study groups4 weeksDepression using Edinburgh Postnatal Depression Scale (EPDS)

Contacts

Primary ContactAhmed Abbas Professor, MD
ahmedabbas@aun.edu.eg+201003385183

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026