Pain Management
Conditions
Brief summary
The local data is insufficient to directly compare IV nalbuphine versus ibuprofen among people in this region. The findings of this study would add to the existing data and would be helpful for health providers to opt for a better option for postoperative pain relief following a cesarean section under general anesthesia.
Interventions
DRUGIbuprofen
Patients were given 800 mg Ibuprofen in 200 cc normal saline intravenously at the time of arrival in the ward.
DRUGNalbuphine
Patients received 20 mg nalbuphine in 200 cc normal saline IV at the time of arrival in the ward.
Sponsors
Muhammad Aamir Latif
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* Parturient females * Aged between 18-45 years * Gestational age above 32 weeks * ASA class I to II * Anticipated hospital stay for at least 24 hours
Exclusion criteria
* Known allergy to the drugs being evaluated in this study * Renal and/or hepatic impairment (as per medical record) * History of bronchial asthma or history or risk of intracranial hemorrhage (as per medical record) * Low platelets count (<70000) or with bleeding diathesis * BMI above 30 kg/m2
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Efficacy in pain control | At 1 hour, 3 hours, and 6 hours. | Outcome was noted in the form of VAS pain scores. Scores from 1 to 3 were labeled as mild pain, 4 to 6 as moderate pain, and 7 to 10 as severe pain. |
Countries
Pakistan
Outcome results
None listed