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Outcome of URS in Fresh Versus Recurrent Cases of Stone Ureter

The Outcome of Ureteroscopy in Fresh Versus Recurrent Cases of Stone Ureter (Post-ESWL, Endoscopy, or Open Surgery)

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06592469
Enrollment
80
Registered
2024-09-19
Start date
2024-10-01
Completion date
2025-11-30
Last updated
2024-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stone Ureter

Keywords

URS

Brief summary

Comparison of Ureteroscopy in fresh versus recurrent cases of stone ureter

Detailed description

Urolithiasis is a common cause of both urology outpatient clinic and emergency room encounters. Approximately 75-90% of ureteral stones pass spontaneously. from this point of view other managements of ureteric stones either ESWL, ureteroscopy or open surgery according to location, site, size, and density. Ureteroscopy is commonly used to diagnose and treat kidney and ureteral stones, ureteral strictures, and urothelial cancers. Semirigid URS is the gold standard of treatment for ureteral stones. High success rates and low morbidity have been reported in semirigid URS. but complications still occur in some cases. The possibility to predict their occurrence should influence patient advisement and better case selection. there are many predictors of successful URS as age, gender, previous ESWL, and stone character. In addition, the impacted stone is a risk factor, and it is described in the literature as ureteral wall thickness, higher grades of hydronephrosis, ureteral stricture, polyp, inflammatory reaction, and difficulty to introduce the guide wire. the literature is very poor in illustrating the previous procedures as a predictor of successful URS only seen in very few original articles as second-time URS after any procedure decreases the rate of success, so it is a point of research that Amr Moustafa aims to clarify. Amr Moustafa will conduct a prospective study to evaluate the outcomes of URS for stones in the fresh and recurrent cases.

Interventions

PROCEDUREUreteroscopy

URS is done to each group to reveal outcome of stone free rate in fresh versus recurrent cases of stone ureter

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* • all cases with middle and lower ureteric stone candidate for endoscopy. * Stone 15mm or less.

Exclusion criteria

* • Patients with a ureteral stent. * Patient refusing participation. * Pregnant woman. * Active urinary tract infection. * Comorbidities prevent intervention including bleeding tendency or uncorrectable coagulation profile.

Design outcomes

Primary

MeasureTime frameDescription
Stone free rate of Urereroscopy in fresh versus recurrent cases of stone ureter1 day post operative by MSCTKUB or Plain KUB to determine residual stones post operative• Stone free rate with a mean operative time of 1 hr by MSCTKUB or Plain KUB to determine residual stones post operative

Secondary

MeasureTime frameDescription
• Rate of intraoperative findings in each group.Intraoperative• Rate intraoperative findings in each group by ureteroscope
• The rate of complication in each groupIntraoperative by ureteroscope and one day post operative by MSCTTo determine rate of intraoperative complications as bleeding , ureteric perforation , residual stones
• The rate of stone impaction in each groupIntraoperative by ureteroscopeRate of stone impaction in each group fresh and recurrent cases

Countries

Egypt

Contacts

Primary ContactAmr Moustafa Hussein Soliman, Resident dr
amr.mustafa303@gmail.com+201140340697

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026