Cataract, Intraocular Lens, Visual Outcomes
Conditions
Brief summary
The objective of this study was to compare the objective visual outcomes and subjective fuctional vision of four different intraocular lens (IOL) in patients underwent cataracts surgery. This was a retrospective study. Patients with age-related cataract underwent phacoemulsification combined with IOLs implantation. Patients were divided into 4 groups. Uncorrected distant visual acuity(UDVA), uncorrected intermediate visual acuity (UIVA), uncorrected near visual acuity (UNVA),and the best corrected visual acuity (BCVA) 1 month and 3 months after the surgery were determined. The defocus curve, contrast sensitivity, and customized VF-14-oriented Visual Function Index questionnaire were performed 3 months postoperatively. Kruskal-Wallis test and generalized estimating equation(GEE) were used to analyze and compare the difference between objective visual outcomes and subjective visual quality among different groups.
Detailed description
The objective of this study was to compare the objective visual outcomes and subjective fuctional vision of four different intraocular lens (IOL) in patients underwent cataracts surgery. This was a retrospective study. Patients with age-related cataract underwent phacoemulsification combined with IOLs implantation. Patients were divided into group A (TECNIS PCB00 IOL), Group B (HumanOptics Diff-Aay IOL), Group C (TECNIS Symfony ZXR00 IOL) and group D (ZEISS AT LISA tri 839MP IOL). Uncorrected distant visual acuity(UDVA), uncorrected intermediate visual acuity (UIVA), uncorrected near visual acuity (UNVA),and the best corrected visual acuity (BCVA) 1 month and 3 months after the surgery were determined. The defocus curve, contrast sensitivity, and customized VF-14-oriented Visual Function Index questionnaire were performed 3 months postoperatively. Kruskal-Wallis test and generalized estimating equation(GEE) were used to analyze and compare the difference between objective visual outcomes and subjective visual quality among different groups.
Interventions
DEVICETECNIS PCB00 intraocular lens
In this study, we select TECNIS PCB00 IOL for inserting in the eyes during the cataract surgery
DEVICEHumanOptics Diff-Aay intraocular lens
In this study, we select HumanOptics Diff-Aay IOL for inserting in the eyes during the cataract surgery
DEVICETECNIS Symfony ZXR00 intraocular len
In this study, we select TECNIS Symfony ZXR00 IOL for inserting in the eyes during the cataract surgery
DEVICEZEISS AT LISA tri 839MP intraocular len
In this study, we select ZEISS AT LISA tri 839MP IOL for inserting in the eyes during the cataract surgery
Sponsors
Shanghai 10th People's Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
50 Years to 95 Years
Healthy volunteers
No
Inclusion criteria
* age-related cataract with myopia≤-6.0D and over 0.0D * axial length≤26mm and corneal astigmatism≤1.5D * well-cooperation of finishing preoperative examinations * completion of all follow-up visits
Exclusion criteria
* previous eye diseases that affect vision including keratopathy, glaucoma, uveitis, amblyopia, fundus diseases, etc. * patients with decreased cognitive ability, unable to cooperate with preoperative examination, or suffering from severe anxiety, depression and mental illness * serious complications during operation, including corneal injury, iris injury, expelling choroidal hemorrhage, posterior capsule rupture, etc * serious postoperative complications, including displacement of intraocular lens, macular edema, endophthalmitis, etc * follow-ups less than 3months
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative visual acuity | 3 months | The uncorrected distant visual acuity(UDVA), the best corrected distant visual acuity (BCVA) (5 m), the uncorrected intermediate visual acuity(UIVA) (80 cm) and the uncorrected near visual acuity(UIVA) (40 cm) were chosen as the index to evaluate the VA. The UDVA and BCVA were examined by logarithmic visual acuity chart. The UIVA and UIVA were examined by using a near eye chart.They were all measured 1 month and 3 months after the surgery. |
| Postoperative contrast sensitivity | 3 months | The contrast sensitivity was used to conduct the assessment by CSV-1000E (VectorVision, USA) under photopic (85 cd/m2) condition at a 2.5m distance. The logarithmic values for 3, 6, 12, and 18 cycles/degree (c/d) were analyzed 3 months postoperatively. |
| Postoperative defocus curve | 3 months | Defocus curve was used to evaluate the visual quality of functional intraocular lens after surgery. The insertion range was -4.0 D \ + 2.0 D, increasing by 0.5 D. The best corrected distant visual acuity was recorded at each diopter 3 months postoperatively. |
| Postoperative eye-related quality of life | 3 months after surgery | Based on the American Questionnaire on Visual Function Index-14 (VF-14), the Chinese-oriented version(VF-12-CN) was used to investigate the postoperative near-vision, visual satisfaction, ocular discomfort, visual disturbance, and subjective feelings of far-vision, middle-vision and near-vision. Each question was divided into 4 levels and the scores ranked from 0 to 3 points. Considering the visual interference such as glare and halo, the evaluation of glare and halo visual interference phenomenon was also added. |
Countries
China
Outcome results
None listed