Hyperglycemia and Acute Pancreatitis

The Risk Factors and Predictors of Hyperglycemia Secondary to Acute Pancreatitis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06590233

Enrollment

4500

Registered

2024-09-19

Start date

2013-01-31

Completion date

2024-08-31

Last updated

2024-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Pancreatitis (AP), Diabetes Mellitus

Keywords

Acute pancreatitis, Diabetes mellitus, PPDM-A, Risk factor

Brief summary

The goal of this observational study is to learn about post-acute pancreatitis diabetes mellitus (PPDM-A). The main questions it aims to answer are: 1. What are the clinical characteristics of PPDM-A? 2. What are the related factors for PPDM-A? All patients with acute pancreatitis have been given standardized treatment for the condition. The researchers will compare the PPDM-A group with the non-PPDM-A group to find the risk factors for PPDM-A.

Detailed description

Investigators retrospectively collected data from patients with acute pancreatitis (AP) in participating centers between January 2013 and June 2024.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

1. Patients with pancreatitis attending participating centers since January 2013 (patients with clinically reported AP (ICD-10:K85 or related diagnosis)); 2. Age between 18 and 80 years; 3. Patients have undergone glucose metabolic tests at least 1 month after discharge from hospital.

Exclusion criteria

1. Patients with a history of diabetes mellitus prior to the AP attack; 2. Patients who underwent pancreatic surgery; 3. Patients with hereditary pancreatitis and autoimmune pancreatitis; 4. Patients with missing data regarding age or gender.

Design outcomes

Primary

Measure	Time frame	Description
Number of participants who have developed PPDM-A	From the AP treatment to 5 years after the end of treatment	PPDM-A was defined as diabetes after AP in the absence of a history of preexisting diabetes before the AP episode.

Outcome results