Alcohol Withdrawal Syndrome
Conditions
Brief summary
The goal of this observational study is to describe the impact measured through the Odds Ratio (OR) of different variables of clinical and biochemical alterations on the duration of the syndrome alcohol withdrawal patients measured in days of symptoms and stay; it could include any patients with a diagnosis of admission of alcohol withdrawal syndrome (AWS) who have been treated in the department of Internal Medicine for 5 years. The main question it aims to answer is: What is the relationship between the different clinical, biochemical, and hematic factors on the duration of symptoms, morbidity, and mortality in individuals with alcohol syndrome withdrawal? • If the patient has a greater number of risk factors, such as advanced age, a long and chronic history of alcohol consumption, the type of distillate consumed, as well as the deterioration of liver function and presence of leukocytosis and neutrophilia, then it is postulated that the duration of alcohol withdrawal syndrome will be longer. Clinical records will be used to describe the proportion of complications associated with alcohol withdrawal syndrome including pneumonia bronchial aspiration, seizures, need for mechanical ventilation, digestive tract hemorrhage, toxic-alcoholic hepatitis, and pancreatitis.
Detailed description
Clinical records (files) of patients with a diagnosis of admission of alcohol withdrawal syndrome (AAS) who have been treated in the Department of Internal Medicine for 5 years.
Interventions
OTHERStudy Cohort
Clinical records (files) of patients with a diagnosis of admission of alcohol withdrawal syndrome (AAS) who have been treated in the Department of Internal Medicine for 5 years.
Sponsors
Hospital General de Mexico
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Clinical records of patients, both genders, over 18 years of age with Alcohol Withdrawal Syndrome according to the criteria for alcohol withdrawal. * Clinical records of candidates for admission for neurological monitoring and with criteria for use of sedative drugs according to the CIWA-Ar scale * Clinical records of patients containing the CIWA-Ar scale score at diagnosis
Exclusion criteria
* Clinical records of patients who already have a history of seizures or epilepsy * Clinical records of diabetic patients with diabetic ketoacidosis * Clinical records of patients who have not received any type of sedative treatment * Clinical records of patients with chronic liver failure or liver cirrhosis * Clinical records of patients with chronic liver disease with signs of hepatic encephalopathy * Clinical records of patients with related toxic-alcoholic hepatitis * Clinical records of patients with a life expectancy of less than 24 hours due to associated complications such as head trauma or other associated complications * Clinical records of patients who require intubation and mechanical ventilation upon admission * Clinical records of patients who have a vascular event that modifies the neurological evaluation * Clinical records of patients who before admission show psychomotor alteration or neurological deterioration that modifies the neurological evaluation such as the presence of Wernicke's encephalopathy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Death | 6 months | Permanent cessation of all vital functions of an organism, including irreversible stopping of the heart and breathing |
| Morbidity | 6 months | Any type of complication present during the analysis period that complicates the resolution of the condition, including serious situations. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hospital stay | 6 months | Time recorded in the clinical record of the duration of symptoms from the first clinical manifestation until the time of discharge. |
| Duration of symptoms | 6 months | Time recorded in the clinical record of the duration of symptoms from the first clinical manifestation to the description of improvement in the medical notes |
Countries
Mexico
Contacts
Primary ContactChristian O Ramos Peñafiel, PhD
Backup ContactYossadara Hernández Ángeles, MD
Outcome results
None listed