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An Investigation of Attentional and Inhibitory Processes During Active Visual Search in Humans

Contributions of Attentional and Inhibitory Functioning to Saccadic Decisions

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06587113
Enrollment
225
Registered
2024-09-19
Start date
2024-09-15
Completion date
2026-05-15
Last updated
2026-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye Movements, Attention, Executive Function

Keywords

Individual differences, Eye movements, Perception, Attention, Inhibition

Brief summary

The goal of this study is to investigate the finding that there are large individual differences in how participants move their eyes during active visual search. For example, some individuals tend to fixate, that is point their eyes steadily at a single location, for longer than other individuals before moving to another location. This experiment will use behavioral tasks to measure an individual's attentional and inhibitory functioning, and then see how each of these contributes to between-participant variability in eye movement behavior during visual search.

Detailed description

To accomplish the goal of understanding the source of individual variability in eye movement patterns, each participant will complete three separate tasks. The first task will require participants to find a target and eye movements will be measured to assess individual differences in fixation duration and other types of eye movement behavior. A second task will evaluate attentional functioning over the visual field by requiring participants to detect briefly-presented targets using their peripheral vision. Finally, a third task will assess inhibitory functioning by having participants attempt to stop eye movements after they have been programmed.

Interventions

OTHERContour Search Task

In this task, participants sit in front of a computer screen with their head in a chinrest to control for distance from the monitor and eye-tracking equipment. For the visual search task, participants will search for a visual target among distractors and make a response regarding its orientation. The target is defined by a contour formed through oriented Gabor patches.

In this task, participants sit in front of a computer screen with their head in a chinrest to control for distance from the monitor and eye-tracking equipment. For the stop-signal task, participants will make an eye movement to a target that appears on the screen, except on trials where a visual signal appears indicating they should cancel this behavior.

BEHAVIORALUseful field of View

In this task, participants sit in front of a computer screen with their head in a chinrest to control for distance from the monitor and eye-tracking equipment. In the useful field of view task, participants will report the location of a briefly-presented and masked target, while also responding to the identify of a central target in some blocks.

BEHAVIORALAttentional capture search task

In this task, participants sit in front of a computer screen with their head in a chinrest to control for distance from the monitor and eye-tracking equipment. For this visual search task, participants will search for a visual target among distractors and make a response regarding its orientation. The target is defined as a unique shape, and is sometimes shown with a salient distractor.

Sponsors

University of Colorado, Denver
Lead SponsorOTHER
National Eye Institute (NEI)
CollaboratorNIH

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE

Intervention model description

Basic Experimental Studies Involving Humans (BESH)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* 18-65 years old

Exclusion criteria

* Self-reported history of neurological illness * Uncorrected vision problems

Design outcomes

Primary

MeasureTime frameDescription
First fixation duration during visual searchDuring visual search taskThis measure is the average first fixation duration during the visual search task. Possible scores are a minimum of 50 ms with an undeterminable positive number of ms as a maximum. This measure indicates the duration of processing before the first eye movement decision.
Fixation count during visual searchDuring visual search taskThis measure is the count the average number of eye movements participants made per trial during the visual search task. Possible scores range from a minimum of 0 to approximately 40 eye movements, given the time available. This measure indicates the amount of active exploration of the display during search.
Stop signal reaction timeDuring inhibitory taskStop signal reaction time is a quantitative estimate of how long participants take to successfully inhibit a planned eye movement. Possible scores range from a minimum of 0 ms to a maximum of about 600 ms. Low scores indicate strong inhibitory ability and high scores indicate weak inhibitory ability.
Useful field of view thresholdingDuring attention taskPerformance in a thresholding task indicates participants ability to detect a briefly presented target among distractors with 80% accuracy. Contrast of the displays varies until performance meets achieved level. Possible scores range from 0 to 100% contrast. Lower contrast indicates better information accrual, while higher contrast indicates worse.
Useful field of view dual task performanceDuring attention taskPerformance in a dual task indicates participants ability to spread attention across the visual field. Possible scores range from 0 to 100% accuracy. Higher performance indicates better information accrual, while lower performance indicates worse.
Oculomotor capture by salient distractorDuring visual search taskin the attentional capture search task, a measure of how often participants look at the salient yet irrelevant distractor will be calculated.

Secondary

MeasureTime frameDescription
Average fixation duration during visual searchDuring the visual search taskThis measure is the average fixation duration across all fixations in a trial during the visual search task. Possible scores range from a minimum of 50 ms to approximately 500 ms. This measure indicates the average duration of processing before a saccadic decision is made.

Countries

United States

Contacts

CONTACTCarly J Principal Investigator, PhD
carly.leonard@ucdenver.edu303-315-7068
CONTACTRyan V Postdoctoral Fellow, PhD
ryan.ringer@ucdenver.edu303-315-7065
PRINCIPAL_INVESTIGATORCarly J Leonard, Phd

University of Colorado enver

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 21, 2026