Idiopathic Pulmonary Arterial Hypertension
Conditions
Brief summary
This study will be performed based on a retrospective analysis of the cases of 150-170 patients with IPAH observed at the Research Institute of Clinical Cardiology over the past 10 years, for a comparative assessment of the survival of groups of patients with IPAH diagnosed in the period 2004-2013 and 2014-2023. The demographic, clinical, functional, hemodynamic characteristics of patients, comorbidity, blood biomarker levels, received PAH-specific and symptomatic therapy will be assessed in order to determine the clinical characteristics of patients with IPAH. The prospective part of study will include 50 patients with IPAH.
Interventions
None listed
Sponsors
Russian Cardiology Research and Production Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* age over 18 years; * verified diagnosis of IPAH
Exclusion criteria
* age under 18 years; * Other etiology op PAH, * ischemic heart disease confirmed by MSCT of the coronary arteries or coronary angiography; * diseases of the musculoskeletal system that prevent 6MWT * severe liver dysfunction (more than 9 points on the Child-Pugh scale, class C) * severe renal dysfunction (CC less than 15 ml/min), need for hemodialysis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality in 3 years after diagnosed IPAH | 3 years |
Countries
Russia
Outcome results
None listed