Rural Smoking Cessation

Evaluating Population-Based Strategies for Rural Smoking Cessation

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06584929

Enrollment

272

Registered

2024-09-05

Start date

2026-05-01

Completion date

2029-08-31

Last updated

2026-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Smoking Cessation

Brief summary

Understanding ways to help people who live in rural areas quit smoking is a public health priority. quitting smoking among rural people who smoke is a critical public health concern. People in rural areas smoke at higher rates than those in urban areas, experience high rates of smoking caused cancers and deaths. We are recruiting rural people from around the country to better understand how different quit smoking methods can improve a person's chances of successfully quitting smoking.

Detailed description

This is a SMART, where eligible rural people who smoke (RPWS) can be randomized up to two times to different resources/ways to help quit smoking. For each randomization, participants will use the assigned resources for 3 months, and partake in surveys at baseline, 1, and 3 months, during which they will be asked several questions related to use of resources, and smoking behavior. Carbon monoxide (CO) in exhaled breath will be collected at 3 months using iCO™ Smokerlyzer® (https://www.icoquit.com/us/) to determine biochemically confirmed abstinence.

Interventions

DRUGNicoderm CQ nicotine patch

Two week supply provided to participants on study.

DRUGNicorette Nicotine Lozenges

Two week supply provided to participants on study.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

21 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* ≥ 21 years * smoke ≥ 5 cigarettes per day * daily access to their own iPhone/Android smartphone or tablet

Exclusion criteria

* past 30-day NRT use or contraindications listed on the NRT labels * currently pregnant/breastfeeding

Design outcomes

Primary

Measure	Time frame	Description
Number of participants abstinent from all combustible tobacco products	3 months	Biochemically-confirmed 7-day abstinence from all combustible tobacco products at 3 months.

Secondary

Measure	Time frame	Description
Cigarettes per day (CPD)	1 and 3 months	Number of cigarettes smoked per day.

Contacts

CONTACTDana Carroll, PhD

dcarroll@umn.edu612-624-4511

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 12, 2026