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Dry Needling Vs Transcutaneous Electrical Nerve Stimulation in Management of Myofascial Pain Dysfunction Syndrome

Comparative Study of Dry Needling Vs Transcutaneous Electrical Nerve Stimulation in Management of Patient with Myofascial Pain Dysfunction Syndrome Using Electromyography and Visual Analogue Scale: a Randomized Clinical Trial

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06583915
Enrollment
26
Registered
2024-09-04
Start date
2024-12-01
Completion date
2025-08-31
Last updated
2024-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myofascial Pain - Dysfunction Syndrome of TMJ

Brief summary

Myofascial pain dysfunction syndrome (MPDS) is the most common form of temporomandibular disorders. Because of the multifactorial nature of the problem, its management is still not definite. This randomized clinical trial aimed to assess the efficacy of transcutaneous electrical nerve stimulation over dry needling for management of such condition.

Detailed description

Myofascial pain syndrome (MPS) is a prevalent affliction among individuals experiencing musculoskeletal pain issues. This condition is characterized by pain originating from the muscle and surrounding fascia. Patients typically exhibit localized pain in a confined region or referred pain with diverse patterns. Additionally, physical examinations may reveal trigger points on the affected muscles. MPS can be categorized into acute and chronic forms. Acute MPS often resolves spontaneously or with uncomplicated treatments. However, chronic MPS typically has a poorer prognosis, and symptoms may persist for six months or more. Dry needling involves the insertion of a solid filiform needle into a trigger point without the administration of any substance. Various theories have been put forth to explain the mechanisms by which dry needling alleviates pain . These include the "gate control" theory, modulation of endogenous opioids such as B-endorphin, encephalins, and dynorphins, disruption of central sensitization through activation of Aβ fibers resulting in inhibition of synaptic transmission between Aβ and C fibers and cells of the spinal cord dorsal horn due to their slower impulse conduction, and even placebo effects have been suggested . When a needle is inserted into a trigger point, it may elicit a local twitch response. This reflexive contraction of the trigger point can also facilitate physiological changes, including the reduction of spontaneous electrical activity and the concentration of inflammatory and nociceptive chemicals, ultimately resulting in the relaxation of the trigger point. Transcutaneous electrical nerve stimulation (TENS) is considered to be a highly secure and cost-effective modality for managing both chronic and acute pain. As per the gate control theory, TENS employs low voltage electrical pulses that are applied to the central nervous system. The modulation of pain perception induced by TENS is attributed to the recruitment of Aβ afferent fibers in the posterior horn of the spinal cord, which prevents the activation of pain conducted in thin fiber. Electrical stimulation effectively inhibits the transmission of painful impulses through the spinal cord and stimulates the release of endogenous opioids by the brain. Its safe, noninvasive, inexpensive and effective method of providing analgesia with reduced potential adverse effects compared to other treatment modalities. In this research, we aim to evaluate TENS is a suitable treatment for MPDS patients, which would eliminate the need for another treatment modality. The expected benefit in this study is to find the best treatment for MPDS reducing pain, muscle stiffness and limited mouth opening.

Interventions

PROCEDURETENS

Non-pharmacological method which is widely used by medical and paramedical professionals for the management of acute and chronic pain using electric pulse generator, lead wires and electrodes.

PROCEDUREDry Needle

Invasive procedure where a fine needle or acupuncture needle is inserted into the skin and muscle.

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
No

Inclusion criteria

1. Patients complaining of pain in muscles of mastication lasting for three months or more. 2. Presence of trigger points in the temporalis, masseter or lateral pterygoid muscle identified by clinical examination and palpation. 3. Average pain severity of at least 4 on a 10-point scale 4. Pain in pre-auricular area, or in the ear during rest or function

Exclusion criteria

1. No previous tempro-mandibular joint (TMJ) surgical intervention 2. Patients with neurological disorders, coagulopathy, vascular disease autoimmune disease (systemic lupus, rheumatoid arthritis), fibromyalgia 3. Pregnancy 4. Current opioid use 5. Intake of analgesics, muscle relaxant, anti-inflammatory medications such as NSAID's and benzodiazepines, 6. Patients with severe trauma or infections in TMJ 7. Tempro-mandibular dysfunction (TMD) with joint origin (any type of internal derangement)

Design outcomes

Primary

MeasureTime frameDescription
PainFrom enrollment to the end of treatment at 6 monthsUsing visual analogue scale (VAS) from (1-10) where 1 is the least pain and 10 is the maximum pain

Secondary

MeasureTime frameDescription
Sleeping disorderFrom enrollment to the end of treatment at 6 monthsAssessing sleeping disorder through Yes or No questionnaire
AnxietyFrom enrollment to the end of treatment at 6 monthsAssessing anxiety through Yes or No questionnaire
Muscle stiffnessFrom enrollment to the end of treatment at 6 monthsusing Electromyography to measure muscle response or electrical activity in response to a nerve stimulation of the muscle (volt)
Limitation in mouth openinigFrom enrollment to the end of treatment at 6 monthsMeasuring muscle opening using digital caliber (Micrometer)
Patient satisfactionFrom enrollment to the end of treatment at 6 monthsAssessing patient satisfaction through Yes or No questionnaire

Contacts

Primary ContactMostafa ElGengehy, PhD
mostafa.elgengehe@dentistry.cu.edu.eg+201221089223

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026