COPD
Conditions
Brief summary
This study aims to assess whether to describe the effects of the administration of nasal high flow (NHF) at 70 liters per minute (L/min) in a 6-Minute Walk Test (6-MWT) among Chronic Obstructive Pulmonary Disease (COPD) patients and to characterize the association between self-reported dyspnea with and without NHF at 70 L/min following a 6-MWT.
Interventions
DEVICENasal High Flow Cannula
High flow nasal cannula is a device that provides heated and humidified high flow gases. In-person. Depending on participant's availability, up to 6 times
DEVICENasal Low Flow Cannula
Low flow nasal cannula is a device that provides low flow gases. In-person. Depending on participant's availability, up to 6 times
Sponsors
University of Miami
American Thoracic Society
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* Able to consent * Age 18 years or older * Diagnosis of COPD * Ability to ambulate without assistance * Use of low-flow nasal cannula ≤ 4 L/min or no supplemental oxygen (O2) at all
Exclusion criteria
* Pregnancy * Being on bedrest * Inability to consent or cooperate with the study * Using of \> 4 L/min of supplemental O2 or requiring non-invasive ventilation during the daytime * Hemodynamic instability (resting heart rate \> 130/minute, systolic blood pressure of ≤ 90 mmHg or ≥ 180 mmHg) * Metal implants in the thoracic regions (pacemakers, Automatic Implantable Cardioverter Defibrillator (AICD), plates, screws, rods, and disc replacements)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 6-minute walk test | 30 minutes | The object of the test is to walk as far as possible for six minutes. The subject will walk at a normal pace around a marked course for six minutes. The distance walked in meters over 6 minutes will be measured. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Breathing measured by the Borg dyspnea scale | 30 minutes | This is a patient self-reported scale to rate the difficulty of breathing. The scale ranges from 0 to 10, where "0" indicated no difficulty breathing, and "10" indicates a maximal breathing difficulty. |
Countries
United States
Contacts
CONTACTSaramaria Afanador Castiblanco, M.D.
PRINCIPAL_INVESTIGATORSaramaria Afanador Castiblanco, M.D.
University of Miami
Outcome results
None listed